Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
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Computational Approaches for the Discovery of Human Proteasome Inhibitors: An OverviewBioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine OriginThe 26S proteasome is a multifaceted target for anti-cancer therapiesSynthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibitionInitial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallographyFellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasomeNatural products as chemical probesAdvances in and applications of proteasome inhibitorsFundamental reaction pathway and free energy profile of proteasome inhibition by syringolin A (SylA).Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbationA unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs.Proteomics guided discovery of flavopeptins: anti-proliferative aldehydes synthesized by a reductase domain-containing non-ribosomal peptide synthetase.Fundamental reaction pathway for peptide metabolism by proteasome: insights from first-principles quantum mechanical/molecular mechanical free energy calculationsNeurotrophic natural products: chemistry and biology.Total Synthesis and Stereochemical Assignment of Nostosin B.Bringing natural products into the fold - exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases.The chemistry and biology of syringolins, glidobactins and cepafungins (syrbactins).Exploiting nature's rich source of proteasome inhibitors as starting points in drug development.Proteasome inhibitors: an expanding army attacking a unique target.Synthesis and pharmacology of proteasome inhibitors.Proteases in Mycobacterium tuberculosis pathogenesis: potential as drug targets.Marine-derived Aspergillus species as a source of bioactive secondary metabolites.Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome systemPharmacophore modeling technique applied for the discovery of proteasome inhibitors.Seven new and two known lipopeptides as well as five known polyketides: the activated production of silent metabolites in a marine-derived fungus by chemical mutagenesis strategy using diethyl sulphate.Fundamental reaction pathway and free energy profile for inhibition of proteasome by Epoxomicin.Antiplasmodial thiostrepton derivatives: proteasome inhibitors with a dual mode of action.Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation.Fellutamide B Synthetic Path Intermediates with in Vitro Neuroactive Function Shows Mood-Elevating Effect in Stress-Induced Zebrafish Model
P2860
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P2860
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@ast
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@en
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@nl
type
label
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@ast
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@en
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@nl
altLabel
Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis
@en
prefLabel
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@ast
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@en
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@nl
P2093
P2860
P1476
Proteasome inhibition by fellutamide B induces nerve growth factor synthesis
@en
P2093
Craig M Crews
John Hines
Margaret Fahnestock
P2860
P304
P356
10.1016/J.CHEMBIOL.2008.03.020
P407
P577
2008-05-01T00:00:00Z