Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
about
VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-deltaConcise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic diseaseDown syndrome: searching for the genetic culpritsNFAT promotes carcinoma invasive migration through glypican-6The Robyn Barst Memorial Lecture: Differences between the fetal, newborn, and adult pulmonary circulations: relevance for age-specific therapies (2013 Grover Conference series)Metastatic mechanisms in follicular cell-derived thyroid cancerNeurological phenotypes for Down syndrome across the life spanSynaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down SyndromeGerminal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About?Herpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPaseIncreased Skin Tumor Incidence and Keratinocyte Hyper-Proliferation in a Mouse Model of Down SyndromeThe vertebrate RCAN gene family: novel insights into evolution, structure and regulationRCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal ApoptosisIntegrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells.A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycleYolk sac tumor of the bilateral basal ganglia in a patient with Down syndrome.A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes.Determining frequent patterns of copy number alterations in cancer.The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome.Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.NFAT proteins: emerging roles in cancer progression.Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4.Massive-scale RNA-Seq analysis of non ribosomal transcriptome in human trisomy 21.Riquiqui and minibrain are regulators of the hippo pathway downstream of Dachsous.Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes.Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory.Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression.Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis.Cyclosporin A promotes tumor angiogenesis in a calcineurin-independent manner by increasing mitochondrial reactive oxygen species.CXM: a new tool for mapping breast cancer risk in the tumor microenvironment.Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.Opposing roles for calcineurin and ATF3 in squamous skin cancer.Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation.Survival and morbidity outcomes for very low birth weight infants with Down syndromeNGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effectDYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.Metastatic dormancy and progression in thyroid cancer: targeting cells in the metastatic frontier.
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P2860
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@ast
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@en
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@nl
type
label
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@ast
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@en
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@nl
prefLabel
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@ast
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@en
Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@nl
P2093
P2860
P3181
P356
P1433
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Down's syndrome suppression of ...... he calcineurin inhibitor DSCR1
@en
P2093
Alexander Zaslavsky
Carmella Britt
In-Hyun Park
Judah Folkman
Julie R Korenberg
Kwan-Hyuck Baek
M William Lensch
Richard J Siarey
Ryan C Lynch
Sam S Yoon
P2860
P2888
P304
P3181
P356
10.1038/NATURE08062
P407
P577
2009-06-25T00:00:00Z
P5875
P6179
1030270548