Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer - sprookjes - yvandenbroek - TriplyDB

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer

http://www.wikidata.org/entity/Q24657355

about

LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers Transglutaminase is a tumor cell and cancer stem cell survival factor Krüppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype In situ protein expression in tumour spheres: development of an immunostaining protocol for confocal microscopy DNA methyltransferases: a novel target for prevention and therapy.KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling.IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L More than markers: biological significance of cancer stem cell-defining molecules.ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer A mechanically-induced colon cancer cell population shows increased metastatic potential.Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia.Cancer stem cells: a novel paradigm for cancer prevention and treatment.Endothelium originated from colorectal cancer stem cells constitute cancer blood vessels Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues CD133-positive cancer stem cells from Colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile.Mantle cell lymphoma activation enhances bortezomib sensitivity.Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer.Doxorubicin-enriched, ALDH(br) mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1 Tackling the cancer stem cells - what challenges do they pose?Cancer stem cells and epithelial ovarian cancer Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on β-catenin.Transcriptional profiling of adult neural stem-like cells from the human brain.A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology?Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival Prognostic value of cancer stem cell marker aldehyde dehydrogenase in ovarian cancer: a meta-analysis Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers Coexpression of EpCAM, CD44 variant isoforms and claudin-7 in anaplastic thyroid carcinoma Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells.A new strategy using ALDHhigh-CD8+T cells to inhibit tumorigenesis.Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.Drug-eluting microarrays to identify effective chemotherapeutic combinations targeting patient-derived cancer stem cells Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival.

P2860

Q21560941-CEC6A70F-0980-4C50-A4D4-6DE8F36C017F Q21562662-489599E6-6FA9-401A-B742-60423600D9F1 Q26799862-9F0C8963-9225-4FAA-90C3-8EA0E51C225C Q28486138-317B5475-1628-47A6-BF6F-304E4BE2E565 Q28538384-53BBC489-FDAB-42E4-9325-22A1FF86A1AB Q30353497-743556D6-0F63-4801-8BE1-5B16A7FC8ECA Q30493990-7EAAE7C0-5BF8-431B-ABDF-9FF0DC18CA98 Q33579896-D30FEC1B-FBA0-4784-8454-7B876B6CFEB7 Q33629500-52CFE376-452E-4181-ACF1-FE218FF52590 Q33655332-A75DF12D-59B6-4F7D-B575-621A756E71A5 Q33661278-30C2A32B-0B30-48A6-9A06-F202176751FA Q33662919-A4E15A22-DA12-4D13-AB4D-6F912D6D2A87 Q33812176-FF2CFCA1-22C6-4ADC-8112-C167110CD0EF Q33836972-C2E61315-E74A-4742-86D1-8D845D86BDC8 Q33867131-03ECAE25-6B12-423F-925B-8FE75B9C9847 Q33873312-76B2FBAA-2E19-465E-AE34-62693F3D8505 Q33906564-E875FB41-3AF7-4397-8DE9-EE7D5B314CC5 Q34026132-9A2C369F-0303-4B56-B11A-9C3C6F01D915 Q34076679-DB79D168-7889-4BA8-8EF0-E012388B4241 Q34170564-1B0932CE-868E-4AB6-AAD8-0C4C0A5637F7 Q34360347-5A4CA163-E267-426B-8F7B-EB1215377FD3 Q34361095-1676D001-1119-4ACA-B4C7-2FC4DC624E98 Q34420393-905F6B34-972F-4DD4-9F3B-D25FC3D2BAB3 Q34486691-30E3F6EE-2A1F-4354-B7BA-0792041CC84F Q34523263-187D7900-4318-4DA6-A242-7D4E35BF069B Q34557441-6BA0793E-3DB5-4357-BC49-A98E876E3B92 Q34610971-8D8E7F2F-F65A-4A85-B794-30F3DEA8E308 Q34712867-468A0477-EA7F-4BD8-9CD7-D66CA571BAD0 Q34718277-F2E86AAA-A490-4BA2-A52E-F9C43B2DFA0F Q34978487-1F8F0B61-DFE7-4D1D-9F8C-86F06A73F63E Q35022205-BBD5C36D-A6DC-46F2-A7DE-DB35B308F7A2 Q35055205-CFBFF527-A480-4191-9607-01E7663D9537 Q35140669-67B0C43D-EBF9-44B0-8AFD-0A954824C0A0 Q35146510-8D57CE4F-969C-4657-9507-D586546D32D0 Q35190005-F50A0F01-4F49-433D-B514-471CF5D3EC46 Q35221936-047BD474-0E26-480D-A82E-F036C1A4E94C Q35412202-6DC5761B-FC87-4259-A8F7-DD457B116856 Q35678181-E11DFB9E-A177-4041-8AC4-9B1DF5D5B9AD Q35754181-ED7D29F3-97D5-435B-BFCA-DE31B10ADD1E Q35858675-5C9B0024-DDC8-465F-A67A-CEEDFCEFBDA4

P2860

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer

http://www.wikidata.org/entity/Q24657355

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@ast

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@en

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@nl

type

label

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@ast

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@en

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@nl

prefLabel

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@ast

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@en

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@nl

P1433

Q24657355-C8A01931-B349-4525-A0F7-7A9229B7C933

P1476

Q24657355-7C87B053-D01C-4BC4-8165-AE759F637FED

P2093

Q24657355-02E4A503-7931-42D1-A3CB-576A35E55FAC

Q24657355-6649D52E-B0B3-476A-B163-804DD369ABDB

Q24657355-9BEF456B-BEB6-4118-A085-E642CF03618A

Q24657355-9C3F12DA-DC4A-4E7B-A323-A3ABF3319994

Q24657355-B333FA8F-61EF-4497-B0BC-F2FBB8DD409C

Q24657355-D5161ED3-CE4D-41FB-A830-ECFFFEB9DAC0

P2860

Q24657355-004FC5E3-5A54-4696-B75B-20C29D80BB04

Q24657355-031816B8-2FC4-4325-9EA9-5933264EB126

Q24657355-0411C3EE-A352-4958-A2DD-6E1FEEF43648

Q24657355-091D464E-1C1C-489E-9E7C-95F9E35ED8C6

Q24657355-17B53A72-2D37-45E2-B9EF-346CE9992236

Q24657355-1919F712-003A-4828-9E2F-3E8057A02371

Q24657355-4A5E3F05-7939-4F2A-A14B-DF514935B90F

Q24657355-4CFBB459-BBE0-421A-95EE-6B83EBDBC79C

Q24657355-4D30E332-7ABA-4942-86F9-A59067014EFF

Q24657355-4D953262-C978-4F51-B126-A45EA9EB3D69

P304

Q24657355-91D63AF9-F904-413B-B443-901968867D72

P31

Q24657355-34B6D446-BEC9-476C-9F8C-0642AA9E6123

P3181

Q24657355-F94EE260-CBD2-4DA0-B85D-C4E5B8D0AC5A

P356

Q24657355-FDE42BB3-EB09-44C1-A513-5C4E3889EB91

P407

Q24657355-7DC6542F-5514-4F7D-BE37-7E7A315ADCEF

P433

Q24657355-D3AD9DF0-2D9D-41CE-90A3-B2265F37EE4E

P478

Q24657355-7924045C-F27B-4571-A6BB-3264110A89B6

P50

Q24657355-DFE84E41-FD7B-4BCB-A8DF-52C4F87B094C

P577

Q24657355-A5423388-ED07-4CEC-9BBD-EFEC97F0F144

P698

Q24657355-F54557BA-4656-4E50-965E-767E217566E2

P932

Q24657355-41B60B38-255D-440B-B3E0-21E2A836B482

P3181

P356

0008-5472.CAN-09-1132

P1433

Cancer Research

P1476

Aldehyde dehydrogenase-express ...... nsition from colitis to cancer

@en

P2093

Dennis A Steindler

http://www.w3.org/2001/XMLSchema#string

Edward W Scott

http://www.w3.org/2001/XMLSchema#string

Henry D Appelman

http://www.w3.org/2001/XMLSchema#string

Joseph E Carpentino

http://www.w3.org/2001/XMLSchema#string

Mark J Hynes

http://www.w3.org/2001/XMLSchema#string

Tong Zheng

http://www.w3.org/2001/XMLSchema#string

P2860

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

Inflammation and cancer

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

The risk of colorectal cancer in ulcerative colitis: a meta-analysis

Phenotypic characterization of human colorectal cancer stem cells

Prospective identification of tumorigenic breast cancer cells

A genetic model for colorectal tumorigenesis

Identification and expansion of human colon-cancer-initiating cells

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

Identification of human brain tumour initiating cells

P304

8208-15

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4268386

http://www.w3.org/2001/XMLSchema#string

P356

10.1158/0008-5472.CAN-09-1132

http://www.w3.org/2001/XMLSchema#string

P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

69

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-10-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19808966

http://www.w3.org/2001/XMLSchema#string

P932

2776663

http://www.w3.org/2001/XMLSchema#string