LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling - sprookjes - yvandenbroek - TriplyDB

LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling

LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling

http://www.wikidata.org/entity/Q24672962

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Regulation of FynT function by dual domain docking on PAG/Cbp SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling T cell antigen recognition at the cell membrane Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells Dynamic spectrum quality assessment and iterative computational analysis of shotgun proteomic data: toward more efficient identification of post-translational modifications, sequence polymorphisms, and novel peptides.Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45 Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions.Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation The ubiquitously expressed Csk adaptor protein Cbp is dispensable for embryogenesis and T-cell development and function PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis Lck regulates the threshold of activation in primary T cells, while both Lck and Fyn contribute to the magnitude of the extracellular signal-related kinase response.Membrane domains in lymphocytes - from lipid rafts to protein scaffolds.Transmembrane adaptor proteins: organizers of immunoreceptor signalling.Molecular interdiction of Src-family kinase signaling in hematopoietic cells.Regulation of T-cell receptor signalling by membrane microdomains.Small molecule inhibition of Csk alters affinity recognition by T cells.Lipid rafts in T cell receptor signalling Tumor-induced disruption of proximal TCR-mediated signal transduction in tumor-infiltrating CD8+ lymphocytes inactivates antitumor effector phase Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT.Signaling defects in anti-tumor T cells Lipid rafts and T-lymphocyte function: implications for autoimmunity.Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor.Transmembrane adaptor proteins positively regulating the activation of lymphocytes.Regulation of the SRC family kinases by Csk.The role of membrane rafts in Lck transport, regulation and signalling in T-cells.PAG--a multipurpose transmembrane adaptor protein.Membrane microdomains in immunoreceptor signaling.Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells.Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.LIME mediates immunological synapse formation through activation of VAV.How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism.Transforming potential of Src family kinases is limited by the cholesterol-enriched membrane microdomain Quantitative analysis of the human T cell palmitome.Csk

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LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling

http://www.wikidata.org/entity/Q24672962

description

2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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Journal of Experimental Medicine

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LIME: a new membrane Raft-asso ...... 4 and CD8 coreceptor signaling

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Burkhart Schraven

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Camilla Merten

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Ivan Hilgert

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Jan Paces

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Jiri Spicka

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Luca Simeoni

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Nadezda Brdicková

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Ondrej Horváth

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Pavla Angelisová

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Stefanie Kliche

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P2860

C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor

SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain

Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)

Regulation of Fyn through translocation of activated Lck into lipid rafts

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling

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1453-1462

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scholarly article

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4812091

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10.1084/JEM.20031484

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10

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198

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14610046

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2194115

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