Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.
about
Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathwayInteraction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancementRobo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeabilityIntegrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor βTetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivoThe lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migrationRETRACTED: TGFβ1 signaling via αVβ6 integrinMolecular underpinnings of corneal angiogenesis: advances over the past decadeLeptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesityActivation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitrop21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migrationFocal adhesion kinase in netrin-1 signalingThe integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cellsEndothelial Cell mTOR Complex-2 Regulates Sprouting AngiogenesisFocal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptorsDecreased cell adhesion promotes angiogenesis in a Pyk2-dependent mannerConditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesisVEGFA-VEGFR2 Signaling PathwayRole of FRNK tyrosine phosphorylation in vascular smooth muscle spreading and migration.Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.FERM domain interaction promotes FAK signaling.Filamin B plays a key role in vascular endothelial growth factor-induced endothelial cell motility through its interaction with Rac-1 and Vav-2.Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits.Structural and mechanical functions of integrins.Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis.Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers.Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasisEndothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway.C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancerFascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathwayFRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth.Regulation of endothelial permeability by Src kinase signaling: vascular leakage versus transcellular transport of drugs and macromolecules.Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.A novel role of vascular endothelial cadherin in modulating c-Src activation and downstream signaling of vascular endothelial growth factorEndothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation.Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation.Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms.Tiny dancers: the integrin-growth factor nexus in angiogenic signaling.
P2860
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P2860
Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Src-mediated coupling of focal ...... helial growth factor signaling
@nl
Src-mediated coupling of focal ...... elial growth factor signaling.
@ast
Src-mediated coupling of focal ...... elial growth factor signaling.
@en
type
label
Src-mediated coupling of focal ...... helial growth factor signaling
@nl
Src-mediated coupling of focal ...... elial growth factor signaling.
@ast
Src-mediated coupling of focal ...... elial growth factor signaling.
@en
prefLabel
Src-mediated coupling of focal ...... helial growth factor signaling
@nl
Src-mediated coupling of focal ...... elial growth factor signaling.
@ast
Src-mediated coupling of focal ...... elial growth factor signaling.
@en
P2093
P2860
P3181
P356
P1476
Src-mediated coupling of focal ...... helial growth factor signaling
@en
P2093
David A Cheresh
David D Schlaepfer
Dean Sheppard
Dwayne G Stupack
John D Hood
Xiaozhu Z Huang
Xose S Puente
P2860
P304
P3181
P356
10.1083/JCB.200109079
P407
P577
2002-04-01T00:00:00Z