Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity - sprookjes - yvandenbroek - TriplyDB

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

http://www.wikidata.org/entity/Q24673740

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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival Characterization of the human sulfatase Sulf1 and its high affinity heparin/heparan sulfate interaction domain Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88 Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2 Human genetic disorders and knockout mice deficient in glycosaminoglycan The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus Glycomics approaches for the bioassay and structural analysis of heparin/heparan sulphates Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells Regulation of intracellular signaling by extracellular glycan remodeling.High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats Glycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2.Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches.Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice Immobilization of heparan sulfate on electrospun meshes to support embryonic stem cell culture and differentiation.Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche Genetic analysis of the heparan modification network in Caenorhabditis elegans Heparan sulfate proteoglycans.Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera.Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking α-l-iduronidase.Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.New negative feedback regulators of Egfr signaling in Drosophila.Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer Overexpression of Sulf2 in idiopathic pulmonary fibrosis Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling.Sulfatase 2 facilitates lymphangiogenesis in breast cancer by regulating VEGF-D.The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer.Heparan sulfate in the regulation of neural differentiation and glioma development.The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.

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P2860

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

http://www.wikidata.org/entity/Q24673740

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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type

label

Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Heparan sulfate 6-O-endosulfat ...... and functional co-operativity

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Catherine L R Merry

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Gerdy Ten Dam

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Ina Kalus

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John T Gallagher

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Kurt von Figura

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Michael Padva

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Rebecca J Baldwin

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Thomas Dierks

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Toin H van Kuppevelt

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William C Lamanna

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P2860

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation

The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Functions of cell surface heparan sulfate proteoglycans

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3151679

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10.1042/BJ20060848

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1

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400

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Kurt von Figura

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