Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells
about
Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512.β2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granulesX-ray structure of the mature ectodomain of phogrinICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATsSynergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5Signaling from the secretory granule to the nucleus: Uhmk1 and PAMSerpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cellsRegulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.Secretory granule membrane protein recycles through multivesicular bodiesLoss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2.Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.Widespread dysregulation of peptide hormone release in mice lacking adaptor protein AP-3.Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application.Dense-core secretory granule biogenesis.Neonatal β cell development in mice and humans is regulated by calcineurin/NFATSystematic proteomic analysis identifies β-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic β-cells.Peptidylgycine α-amidating monooxygenase and copper: a gene-nutrient interaction critical to nervous system function.Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growthRapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells.Secretory granule to the nucleus: role of a multiply phosphorylated intrinsically unstructured domain.Senp2 expression was induced by chronic glucose stimulation in INS1 cells, and it was required for the associated induction of Ccnd1 and Mafa.Signaling from the secretory granule to the nucleus.Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.Regulation of β-cell function by RNA-binding proteins.Islet Autoantibodies.Age-dependent labeling and imaging of insulin secretory granules.The Roles of SUMO in Metabolic Regulation.CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells.An extended tyrosine-targeting motif for endocytosis and recycling of the dense-core vesicle membrane protein phogrin.Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum.SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.[Arfaptine-1 controls secretory granule biogenesis].Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.
P2860
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P2860
Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@ast
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@en
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@nl
type
label
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@ast
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@en
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@nl
prefLabel
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@ast
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@en
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@nl
P2093
P2860
P921
P3181
P356
P1476
Nuclear translocation of an IC ...... lin expression in {beta}-cells
@en
P2093
Anke Altkrüger
Hassan Mziaut
Joke Ouwendijk
Klaus-Peter Knoch
Michele Solimena
Mirko Trajkovski
Stefan Müller
P2860
P304
P3181
P356
10.1083/JCB.200408172
P407
P577
2004-12-20T00:00:00Z