Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)
about
Update of the NAD(P)H:quinone oxidoreductase (NQO) gene familyKinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)X-ray structural studies of quinone reductase 2 nanomolar range inhibitorsStructural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductaseCrystal structure of quinone reductase 2 in complex with resveratrolInactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.Resveratrol derivatives: a patent review (2009 - 2012).NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomasCircadian rhythms, oxidative stress, and antioxidative defense mechanisms.My passion for biologics: from active sites to life-saving and public health.Quinone reductases multitasking in the metabolic world.Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?Quinone reductase 2 is a catechol quinone reductaseNRH:quinone oxidoreductase 2 (NQO2) protein competes with the 20 S proteasome to stabilize transcription factor CCAAT enhancer-binding protein α (C/EBPα), leading to protection against γ radiation-induced myeloproliferative disease.Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.NAD(P)H: quinone oxidoreductase 1 and its potential protective role in cardiovascular diseases and related conditions.Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Characterization of the mechanism of inhibition in both cell-free and cellular systems.NAD(P)H:Quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity.Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3.Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.Antioxidant and Quinone Reductase Activity of Soyasaponins in Hepa1c1c7 Mouse Hepatocarcinoma Cells.The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2).Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.
P2860
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P2860
Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@ast
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@en
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@nl
type
label
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@ast
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@en
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@nl
prefLabel
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@ast
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@en
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@nl
P2093
P2860
P356
P1476
Unexpected genetic and structu ...... none reductase (DT-diaphorase)
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.5.1669
P407
P577
1997-03-04T00:00:00Z