MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein - sprookjes - yvandenbroek - TriplyDB

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

http://www.wikidata.org/entity/Q24679773

about

Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1 In vitro nuclear interactome of the HIV-1 Tat protein Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression New insight into the molecular mechanisms of MLL-associated leukemia The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10 Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Partners in crime: The role of tandem modules in gene transcription Diverse functions of PHD fingers of the MLL/KMT2 subfamily BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1 Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression.The Polycomb protein and E3 ubiquitin ligase Ring1B harbors an IRES in its highly conserved 5' UTR Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines.Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis MLL associates specifically with a subset of transcriptionally active target genes.The roles of peptidyl-proline isomerases in gene regulation.Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.The MLL recombinome of acute leukemias in 2013.C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer.Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16.Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues Prolyl isomerases in gene transcription Linking the epigenetic 'language' of covalent histone modifications to cancer.MLL fusions: pathways to leukemia The pathogenesis of mixed-lineage leukemia.Predicting the effect of transcription therapy in hematologic malignancies.The Arabidopsis homologs of trithorax (ATX1) and enhancer of zeste (CLF) establish 'bivalent chromatin marks' at the silent AGAMOUS locus.MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

P2860

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P2860

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

http://www.wikidata.org/entity/Q24679773

description

2003 nî lūn-bûn

@nan

2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

MLL repression domain interact ...... sor C-terminal-binding protein

@ast

MLL repression domain interact ...... sor C-terminal-binding protein

@en

MLL repression domain interact ...... sor C-terminal-binding protein

@nl

type

label

MLL repression domain interact ...... sor C-terminal-binding protein

@ast

MLL repression domain interact ...... sor C-terminal-binding protein

@en

MLL repression domain interact ...... sor C-terminal-binding protein

@nl

prefLabel

MLL repression domain interact ...... sor C-terminal-binding protein

@ast

MLL repression domain interact ...... sor C-terminal-binding protein

@en

MLL repression domain interact ...... sor C-terminal-binding protein

@nl

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PNAS.1436338100

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

MLL repression domain interact ...... sor C-terminal-binding protein

@en

P2093

Manuel O Diaz

http://www.w3.org/2001/XMLSchema#string

Melanie Anderson

http://www.w3.org/2001/XMLSchema#string

Nancy J Zeleznik-Le

http://www.w3.org/2001/XMLSchema#string

Zhen-Biao Xia

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of a family of mammalian methyl-CpG binding proteins

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor

Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.

Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

P304

8342-7

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scholarly article

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4849407

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10.1073/PNAS.1436338100

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14

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P478

100

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2003-07-08T00:00:00Z

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10687743

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P698

12829790

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166231

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