Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families
about
Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancerTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaProtein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patientsMild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences.Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 yearsBiallelic mutations in CAD, impair de novo pyrimidine biosynthesis and decrease glycosylation precursors.Purine and pyrimidine pathways as targets in Plasmodium falciparum.Predictive diagnostics in colorectal cancer: impact of genetic polymorphisms on individual outcomes and treatment with fluoropyrimidine-based chemotherapy.Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum.Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.Crystallization and preliminary X-ray diffraction analysis of orotate phosphoribosyltransferase from the human malaria parasite Plasmodium falciparum.orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphateorotidine 5'-monophosphate => uridine 5'-monophosphate + CO2
P2860
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P2860
Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular cloning of the human ...... itary orotic aciduria families
@ast
Molecular cloning of the human ...... itary orotic aciduria families
@en
Molecular cloning of the human ...... itary orotic aciduria families
@nl
type
label
Molecular cloning of the human ...... itary orotic aciduria families
@ast
Molecular cloning of the human ...... itary orotic aciduria families
@en
Molecular cloning of the human ...... itary orotic aciduria families
@nl
prefLabel
Molecular cloning of the human ...... itary orotic aciduria families
@ast
Molecular cloning of the human ...... itary orotic aciduria families
@en
Molecular cloning of the human ...... itary orotic aciduria families
@nl
P2093
P2860
P1476
Molecular cloning of the human ...... itary orotic aciduria families
@en
P2093
M E Hodgson
P2860
P304
P407
P577
1997-03-01T00:00:00Z