Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation - sprookjes - yvandenbroek - TriplyDB

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

http://www.wikidata.org/entity/Q24682735

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Vitamin B and its derivatives for diabetic kidney disease Vitamin B and/or its derivatives for diabetic kidney disease Hexosamines, insulin resistance, and the complications of diabetes: current status.O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability Coadjuvants in the Diabetic Complications: Nutraceuticals and Drugs with Pleiotropic Effects Acarbose: safe and effective for lowering postprandial hyperglycaemia and improving cardiovascular outcomes A systematic review of type 2 diabetes mellitus and hypertension in imaging studies of cognitive aging: time to establish new norms Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease Lipids and the endothelium: bidirectional interactions Toxic stress, inflammation and symptomatology of chronic complications in diabetes Molecular mechanisms of diabetic retinopathy, general preventive strategies, and novel therapeutic targets Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass O-GlcNAcylation and oxidation of proteins: is signalling in the cardiovascular system becoming sweeter?Hyperglycemia-associated alterations in cellular signaling and dysregulated mitochondrial bioenergetics in human metabolic disorders The Effect of Bariatric Surgery on Diabetic Retinopathy: Good, Bad, or Both?Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site TGF-beta: a crucial component of the pathogenesis of diabetic nephropathy Mitochondrial morphology in metabolic diseases Mitochondrial dysfunction in diabetic cardiomyopathy Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells Redox regulation of endothelial cell fate Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury Alteration of renal respiratory Complex-III during experimental type-1 diabetes O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2 A possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemia Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?Oxidative stress and diabetic complications New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain.Restless legs syndrome and cardiovascular disease: a research roadmap.Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function.Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells.Mechanisms by which diabetes increases cardiovascular disease.

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P2860

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

http://www.wikidata.org/entity/Q24682735

description

2000 nî lūn-bûn

@nan

2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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type

label

Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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prefLabel

Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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Proceedings of the National Academy of Sciences of the United States of America

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Hyperglycemia-induced mitochon ...... y increasing Sp1 glycosylation

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D Edelstein

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H Goldberg

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P2860

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

Association of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production

Preventive effect of long-term aldose reductase inhibition (ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic Bio-Breeding rat

Advanced protein glycosylation in diabetes and aging.

Protein kinase C activation and the development of diabetic complications.

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

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