CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease
about
The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complexControl of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPsIdentification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNAEndoribonucleases--enzymes gaining spotlight in mRNA metabolism.TTS mapping: integrative WEB tool for analysis of triplex formation target DNA sequences, G-quadruplets and non-protein coding regulatory DNA elements in the human genomeAssessing specific oligonucleotides and small molecule antibiotics for the ability to inhibit the CRD-BP-CD44 RNA interaction.The regulation of mRNA stability in mammalian cells: 2.0.Role of the RNA-binding protein IMP-2 in muscle cell motility.Molecular insights into the coding region determinant-binding protein-RNA interaction through site-directed mutagenesis in the heterogeneous nuclear ribonucleoprotein-K-homology domains.Transcriptional Regulation of CRD-BP by c-myc: Implications for c-myc FunctionsHigh-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.MicroRNA-873 (miRNA-873) inhibits glioblastoma tumorigenesis and metastasis by suppressing the expression of IGF2BP1.Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability.Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1.Characterizing the Coding Region Determinant-Binding Protein (CRD-BP)-Microphthalmia-associated Transcription Factor (MITF) mRNA interaction.Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxiamRNA stability and cancer: an emerging link?Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs.Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism.MicroRNA: a prognostic biomarker and a possible druggable target for circumventing multidrug resistance in cancer chemotherapyInhibition of GLI1 Expression by Targeting the CRD-BP-GLI1 mRNA Interaction Using a Specific Oligonucleotide.miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma.Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents.Near-infrared (NIR) dye-labeled RNAs identify binding of ZBP1 to the noncoding Y3-RNA.Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA.A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation.CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation.Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).A Synechocystis LexA-orthologue binds direct repeats in target genes.SRC increases MYC mRNA expression in ER+ breast cancer via mRNA stabilization and inhibition of p53 function.Abrogating the interplay between IGF2BP1, 2 and 3 and IGF1R by let-7i arrests hepatocellular carcinoma growth.Cross-Talk between Wnt and Hh Signaling Pathways in the Pathology of Basal Cell Carcinoma.Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma
P2860
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P2860
CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@ast
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@en
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@nl
type
label
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@ast
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@en
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@nl
prefLabel
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@ast
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@en
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@nl
P2860
P356
P1476
CRD-BP shields c-myc and MDR-1 ...... y a mammalian endoribonuclease
@en
P2093
Chow H Lee
Dan Sparanese
P2860
P304
P356
10.1093/NAR/GKL1148
P407
P577
2007-01-01T00:00:00Z