PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
about
Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cellsCold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fatVEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinaseSIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidationPGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseThe transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscleNaringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistanceFGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation responseSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisReceptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alphaOrphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesisRole of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolismMitochondrial Quality Control and Muscle Mass MaintenanceThe Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for TreatmentElectron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsRoad to exercise mimetics: targeting nuclear receptors in skeletal muscleRegulation of metabolism: the circadian clock dictates the timeCalcineurin inhibition and new-onset diabetes mellitus after transplantationNew insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyondTranscriptional integration of mitochondrial biogenesisPGC-1α, mitochondrial dysfunction, and Huntington's diseasePGC-1 proteins and heart failureModulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modificationsAdipose tissues and thyroid hormonesRole of mitochondria in nonalcoholic fatty liver diseaseRosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1αAblation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performanceThe protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathwayMitochondrial dysfunction in neurodegenerative diseasesArctigenin efficiently enhanced sedentary mice treadmill enduranceA cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesisPAS kinase is required for normal cellular energy balanceA stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in musclePyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat dietSirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesisSuppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesisExercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissueAcute exercise modulates the Foxo1/PGC-1alpha pathway in the liver of diet-induced obesity ratsRegulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)PGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinase
P2860
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P2860
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@ast
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@en
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@nl
type
label
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@ast
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@en
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@nl
prefLabel
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@ast
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@en
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@nl
P2093
P2860
P50
P3181
P1433
P1476
PGC-1alpha deficiency causes m ...... control and hepatic steatosis
@en
P2093
Brian N Finck
Carlos Bernal-Mizrachi
Daniel P Kelly
David F Wozniak
E Dale Abel
Jeffrey E Saffitz
John J Lehman
John O Holloszy
Michael Courtois
Nandakumar Sambandam
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0030101
P407
P577
2005-04-01T00:00:00Z