PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis - sprookjes - yvandenbroek - TriplyDB

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

http://www.wikidata.org/entity/Q24798075

about

Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation PGC-1 coactivators: inducible regulators of energy metabolism in health and disease The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alpha Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism Mitochondrial Quality Control and Muscle Mass Maintenance The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial Bioenergetics Road to exercise mimetics: targeting nuclear receptors in skeletal muscle Regulation of metabolism: the circadian clock dictates the time Calcineurin inhibition and new-onset diabetes mellitus after transplantation New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond Transcriptional integration of mitochondrial biogenesis PGC-1α, mitochondrial dysfunction, and Huntington's disease PGC-1 proteins and heart failure Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications Adipose tissues and thyroid hormones Role of mitochondria in nonalcoholic fatty liver disease Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway Mitochondrial dysfunction in neurodegenerative diseases Arctigenin efficiently enhanced sedentary mice treadmill endurance A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis PAS kinase is required for normal cellular energy balance A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis Exercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissue Acute exercise modulates the Foxo1/PGC-1alpha pathway in the liver of diet-induced obesity rats Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)PGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinase

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

http://www.wikidata.org/entity/Q24798075

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2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年论文

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Carlos Bernal-Mizrachi

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P2860

PGC-1, a versatile coactivator

The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells

Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

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