The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway
about
Functional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3beta signalingEssential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.Diabetes outfoxed by GLP-1?A comprehensive pathway map of epidermal growth factor receptor signalingAssessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their related metastases on tissue sections and tissue microarrayTargeting of erbB3 receptor to overcome resistance in cancer treatmentEGF receptor trafficking: consequences for signaling and cancerVinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface.EGFR Tyrosine 845 Phosphorylation-Dependent Proliferation and Transformation of Breast Cancer Cells Require Activation of p38 MAPK.Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild typeAlterations in cell growth and signaling in ErbB3 binding protein-1 (Ebp1) deficient miceERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.Epidermal Growth Factor Receptor Cell Proliferation Signaling PathwaysGrowth factor signaling in vitreous humor-induced lens fiber differentiation.Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathwayKey roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth.Protein tyrosine phosphatases as potential therapeutic targets.Odin (ANKS1A) modulates EGF receptor recycling and stability.Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.The epidermal growth factor receptor family: biology driving targeted therapeutics.Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways.Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathwaySuppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membraneDynamic Modeling and Analysis of the Cross-Talk between Insulin/AKT and MAPK/ERK Signaling Pathways.Epidermal growth factor-stimulated Akt phosphorylation requires clathrin or ErbB2 but not receptor endocytosisPredictive and prognostic molecular markers for cholangiocarcinoma in Han Chinese populationCompartmentalizing proximal FGFR1 signaling in ovine placental artery endothelial cell caveolae.Role of GRB2-associated binder 1 in epidermal growth factor receptor-induced signaling in head and neck squamous cell carcinoma.Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liverSTAT3-mediated coincidence detection regulates noncanonical immediate early gene induction.Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina.The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants.Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.Alternate paths from epidermal growth factor receptor to Akt in malignant versus nontransformed lung epithelial cells: ErbB3 versus Gab1.Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts.RGS16 inhibits breast cancer cell growth by mitigating phosphatidylinositol 3-kinase signaling.
P2860
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P2860
The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway
description
2004 nî lūn-bûn
@nan
2004 թուականին հրատարակուած գիտական յօդուած
@hyw
2004 թվականին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@ast
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@en
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@nl
type
label
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@ast
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@en
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@nl
prefLabel
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@ast
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@en
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@nl
P2093
P2860
P3181
P356
P1433
P1476
The docking protein Gab1 is th ...... I-3K/Akt cell survival pathway
@en
P2093
Betty Lamothe
Dawn R Mattoon
P2860
P2888
P3181
P356
10.1186/1741-7007-2-24
P407
P577
2004-01-01T00:00:00Z
P5875
P6179
1002798950