Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein.
about
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's diseaseβ-Amyloid: the key peptide in the pathogenesis of Alzheimer's diseaseDynamin 1 regulates amyloid generation through modulation of BACE-1APP processing in Alzheimer's diseaseTrafficking and proteolytic processing of APPSmall molecule suppressors of Drosophila kinesin deficiency rescue motor axon development in a zebrafish model of spinal muscular atrophyMultiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP)Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesisAxonal transport and neurodegenerative disease: can we see the elephant?Endocytosis and signalling: intertwining molecular networksCalsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport.Genetics of dementia.Mitochondrial dysfunction and cellular metabolic deficiency in Alzheimer's diseaseDeficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.Inhibition of beta-secretase in vivo via antibody binding to unique loops (D and F) of BACE1.Amyloid-β as a modulator of synaptic plasticityDistinct internalization pathways of human amylin monomers and its cytotoxic oligomers in pancreatic cellsGenome-Wide Analyses of Working-Memory Ability: A Review.ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's diseaseAmyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi networkSorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.Ectodomain shedding of the amyloid precursor protein: cellular control mechanisms and novel modifiers.Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivoNumb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesisExpression and processing of fluorescent fusion proteins of amyloid precursor protein (APP).Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsThe comorbidity of HIV-associated neurocognitive disorders and Alzheimer's disease: a foreseeable medical challenge in post-HAART eraTranslational gene mapping of cognitive declineNeprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseasePhosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport.APP Function and Lipids: A Bidirectional Link.Intracellular cholesterol homeostasis and amyloid precursor protein processing.Aspects of beta-amyloid as a biomarker for Alzheimer's disease.Alzheimer's disease genetics: current knowledge and future challenges.The many substrates of presenilin/γ-secretase.Retromers in Alzheimer's disease.Lessons from genome-wide association studies findings in Alzheimer's disease.
P2860
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P2860
Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Inhibition of dynamin-dependen ...... ration of amyloid beta protein
@nl
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@ast
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@en
type
label
Inhibition of dynamin-dependen ...... ration of amyloid beta protein
@nl
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@ast
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@en
prefLabel
Inhibition of dynamin-dependen ...... ration of amyloid beta protein
@nl
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@ast
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@en
P2093
P2860
P3181
P356
P1433
P1476
Inhibition of dynamin-dependen ...... ation of amyloid beta protein.
@en
P2093
Barbara E Slack
Brigitte A Balcz
Ignacio Lopez-Coviella
Robyn M Carey
P2860
P2888
P3181
P356
10.1186/1471-2121-6-30
P407
P577
2005-08-11T00:00:00Z
P5875
P6179
1020767769