Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
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Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cellsSynaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesSynaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseNeurotransmitter release: the last millisecond in the life of a synaptic vesicleCalcium control of neurotransmitter releasePush-and-pull regulation of the fusion pore by synaptotagmin-7Cell biology of Ca2+-triggered exocytosisNeuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretionStructural and mutational analysis of functional differentiation between synaptotagmins-1 and -7Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreasGenetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosisPancreatic regulation of glucose homeostasisThe functional significance of synaptotagmin diversity in neuroendocrine secretionDistinct initial SNARE configurations underlying the diversity of exocytosisLateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretionThe calcium sensor synaptotagmin 7 is required for synaptic facilitationImpaired glucose tolerance in a mouse model of sidt2 deficiencyPalmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomesSilence of Synaptotagmin VII inhibits release of dense core vesicles in PC12 cells.Peptidergic cell-specific synaptotagmins in Drosophila: localization to dense-core granules and regulation by the bHLH protein DIMMED.An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.Autophagy is involved in adipogenic differentiation by repressesing proteasome-dependent PPARγ2 degradationA manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology.Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptorMice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cellsGlucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas.Golgi apparatus-localized synaptotagmin 2 is required for unconventional secretion in Arabidopsis.Differential patterns of synaptotagmin7 mRNA expression in rats with kainate- and pilocarpine-induced seizures.Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic β-cellsMicroarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic β cell line MIN6.Altered islet morphology but normal islet secretory function in vitro in a mouse model with microvascular alterations in the pancreasGelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.The genetic architecture of NAFLD among inbred strains of miceSyntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells.Imaging metabolic syndrome.Dual functions of adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1) in insulin signaling and insulin secretion.
P2860
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P2860
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@ast
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@en
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@nl
type
label
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@ast
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@en
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@nl
prefLabel
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@ast
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@en
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@nl
P2093
P2860
P3181
P356
P1476
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
@en
P2093
Anton Maximov
Elena Kostromina
George K Radda
Jen-Chieh Chuang
Joyce J Repa
Weiping Han
P2860
P304
P3181
P356
10.1073/PNAS.0711700105
P407
P577
2008-03-11T00:00:00Z