The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes
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Wolfram Syndrome: Diagnosis, Management, and TreatmentConsiderations for Defining Cytokine Dose, Duration, and Milieu That Are Appropriate for Modeling Chronic Low-Grade Inflammation in Type 2 DiabetesStress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic isletsIncreased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet functionCirculating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death.Calcium and phosphate concentrations and future development of type 2 diabetes: the Insulin Resistance Atherosclerosis StudyPancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes.Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores.Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.Colchicine to decrease NLRP3-activated inflammation and improve obesity-related metabolic dysregulation.An Automated Perifusion System for Modifying Cell Culture Conditions over Time.Imaging beta-cell mass and function in situ and in vivo.Glucose-induced inhibition of insulin secretion.Selected terpenoids from medicinal plants modulate endoplasmic reticulum stress in metabolic disorders.Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells.Endoplasmic reticulum stress in beta cells and autoimmune diabetes.Pancreatic islet inflammation: an emerging role for chemokines.TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis.Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.SERCA control of cell death and survival.Tributyltin exposure at noncytotoxic doses dysregulates pancreatic β-cell function in vitro and in vivo.Combining fragment homology modeling with molecular dynamics aims at prediction of Ca²⁺ binding sites in CaBPs.Cytokine-mediated changes in K+ channel activity promotes an adaptive Ca2+ response that sustains β-cell insulin secretion during inflammation.Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.
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P2860
The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes
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2011 nî lūn-bûn
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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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The central role of calcium in ...... for type 1 and type 2 diabetes
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Christina M O'Neill
James W Ramadan
Stephen R Steiner
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10.1016/J.CECA.2011.08.005
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2011-09-23T00:00:00Z