Confronting the challenges of discovery of novel antibacterial agents
about
Endless Resistance. Endless Antibiotics?Antibiotics in the clinical pipeline at the end of 2015.Statistical research on the bioactivity of new marine natural products discovered during the 28 years from 1985 to 2012.Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors.Equisetin, reutericyclin and streptolodygin as natural product lead structures for novel antibiotic libraries.Pharmacodynamic Profile of GSK2140944 against Methicillin-Resistant Staphylococcus aureus in a Murine Lung Infection ModelRethinking the Antibiotic Discovery ParadigmLpxC inhibitors: a patent review (2010-2016).In vitro biological evaluation of novel broad-spectrum isothiazolone inhibitors of bacterial type II topoisomerases.Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria.Recent Advances in the Rational Design and Optimization of Antibacterial Agents.Polishing the tarnished silver bullet: the quest for new antibiotics.Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV."When the Bug Cannot Be Killed"-The Rising Challenge of Antimicrobial Resistance.Synergistic Response of Rifampicin with Hydroperoxides on Mycobacterium: A Mechanistic Study.Conformational properties, membrane interaction, and antibacterial activity of the peptaibiotic chalciporin A: Multitechnique spectroscopic and biophysical investigations on the natural compound and labeled analogs.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Novel Bacterial Topoisomerase Inhibitors Exploit Asp83 and the Intrinsic Flexibility of the DNA Gyrase Binding Site.Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.Mimics of pramanicin derived from pyroglutamic acid and their antibacterial activity.Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria.Activation of microbial secondary metabolic pathways: Avenues and challenges
P2860
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P2860
Confronting the challenges of discovery of novel antibacterial agents
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Confronting the challenges of discovery of novel antibacterial agents
@ast
Confronting the challenges of discovery of novel antibacterial agents
@en
Confronting the challenges of discovery of novel antibacterial agents
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type
label
Confronting the challenges of discovery of novel antibacterial agents
@ast
Confronting the challenges of discovery of novel antibacterial agents
@en
Confronting the challenges of discovery of novel antibacterial agents
@nl
prefLabel
Confronting the challenges of discovery of novel antibacterial agents
@ast
Confronting the challenges of discovery of novel antibacterial agents
@en
Confronting the challenges of discovery of novel antibacterial agents
@nl
P1476
Confronting the challenges of discovery of novel antibacterial agents
@en
P2093
Sheo B. Singh
P304
P356
10.1016/J.BMCL.2014.06.053
P407
P577
2014-08-15T00:00:00Z