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about
sameAs
Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replicationInsig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitroCharacterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteinsCrucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ERInsig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteinsNPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomesJuxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasisLiver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesisRichard G.W. Anderson (1940-2011) and the birth of receptor-mediated endocytosisGhrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted miceHair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatinOverexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesisCholesterol feedback: from Schoenheimer's bottle to Scap's MELADLThe LDL receptorCombined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genesSterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to InsigSterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteinsCholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphilesStructure of the LDL receptor extracellular domain at endosomal pHStructure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of CholesterolReconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and InsigsMembrane topology of human insig-1, a protein regulator of lipid synthesisAccelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domainIdentification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormoneCompensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liverSchoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteinsSevere facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatinLXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle sizeBifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesisGhrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis.Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change.Medicine. HDL miR-ed down by SREBP introns.Lasker Awards 2002. Foreword: synergy and symbiosis à la Matisse-Picasso.Lasker awards 2003. Foreword: It's a grand year for celebrating science.Scientific side trips: six excursions from the beaten path.Towering science: an ounce of creativity is worth a ton of impact.Juxtapositions in Trafalgar Square: tip-offs to creativity in art and science.Balzac's Unknown Masterpiece: spotting the next big thing in art and science.60 years of winged victories for biomedical research.
P50
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P50
description
Amerikaans klinische genetica
@nl
Amerikalı biyokimyacı ve genetikçi
@tr
US-amerikanischer Genetiker
@de
amerykański genetyk, noblista
@pl
biochimico e genetista statunitense
@it
dokter asal Amerika Serikat
@id
eolaí
@ga
scientist
@en
دانشمند و بیوشیمیدان آمریکایی
@fa
美国生化学家和遗传学家
@zh
name
Goldstayn Jozef Leonard
@uz
Ioseph Leonardus Goldstein
@la
Joseph Goldstein
@fr
Joseph Goldstein
@it
Joseph Goldstein
@nl
Joseph Goldstein
@pt
Joseph Goldstein
@sw
Joseph L. Goldstein
@cs
Joseph L. Goldstein
@cy
Joseph L. Goldstein
@da
type
label
Goldstayn Jozef Leonard
@uz
Ioseph Leonardus Goldstein
@la
Joseph Goldstein
@fr
Joseph Goldstein
@it
Joseph Goldstein
@nl
Joseph Goldstein
@pt
Joseph Goldstein
@sw
Joseph L. Goldstein
@cs
Joseph L. Goldstein
@cy
Joseph L. Goldstein
@da
altLabel
Broken/Joseph L. Goldstein
@fi
Goldstein J
@en
Goldstein J. L.
@en
Goldstein J.
@en
Goldstein JL
@en
Goldstein Joseph L.
@fi
Goldstein
@en
Goldstein, Joseph L.
@sv
J Goldstein
@en
J L Goldstein
@en
prefLabel
Goldstayn Jozef Leonard
@uz
Ioseph Leonardus Goldstein
@la
Joseph Goldstein
@fr
Joseph Goldstein
@it
Joseph Goldstein
@nl
Joseph Goldstein
@pt
Joseph Goldstein
@sw
Joseph L. Goldstein
@cs
Joseph L. Goldstein
@cy
Joseph L. Goldstein
@da