about
P2176
P3781
Effect of rifampicin on the pharmacokinetics of lenvatinib in healthy adults.Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer modelsE7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts.A review of 2014 cancer drug approvals, with a look at 2015 and beyond.A phase 2 trial of lenvatinib (E7080) in advanced, progressive, radioiodine-refractory, differentiated thyroid cancer: A clinical outcomes and biomarker assessmentA phase 1b clinical trial of the multi-targeted tyrosine kinase inhibitor lenvatinib (E7080) in combination with everolimus for treatment of metastatic renal cell carcinoma (RCC).Lenvatinib: first global approval.Anticancer effect of COX-2 inhibitor DuP-697 alone and in combination with tyrosine kinase inhibitor (E7080) on colon cancer cell lines.A validated LC-MS/MS method of total and unbound lenvatinib quantification in human serum for protein binding studies by equilibrium dialysis.Effect of lenvatinib (E7080) on the QTc interval: results from a thorough QT study in healthy volunteers.Evaluation of the effects of formulation and food on the pharmacokinetics of lenvatinib (E7080) in healthy volunteers.Pharmaceutical approval update
P921
Q34085125-AFA852F0-A8A4-4BCA-A857-38F16B8B30F6Q34253418-F5B57943-154D-4EBD-9870-EC2DD96FE739Q34558883-76BC0EFF-770C-4408-A707-C510ADC0B61DQ35170573-7216742E-51D5-4A0B-B2BD-E81C0C857901Q36716739-E71B7BA0-A8AA-409A-A160-76A764FFCAB2Q37470131-C199D627-5D8A-4B2E-9C6F-00FECA6580A4Q38385844-F7AA2413-E880-4B86-B038-3E3959A0BB1EQ38996358-EF3FDDDF-8BBC-403D-8CEB-88A2160814D0Q54269091-9CAE9F81-C94E-4153-A282-F5F1B73568F2Q54365531-7F0BC7DA-0E73-4941-9DAC-C4712B9FCB9AQ54376408-670DF3B8-B2A6-4770-8C8B-8E0D33E07997Q94372309-CBB90656-3BA2-487F-A3CB-D1BF0803EE8E
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
lenvatinib mesylate
@en
lenvatinibmesylat
@nn
type
label
lenvatinib mesylate
@en
lenvatinibmesylat
@nn
altLabel
E7080
@en
Lenvatinib mesilate
@en
N-(4-((6-Carbamoyl-7-methoxyqu ...... ropylurea monomethanesulfonate
@en
UNII-3J78384F61
@en
lenvatinibmesilat
@nn
prefLabel
lenvatinib mesylate
@en
lenvatinibmesylat
@nn
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857890-39-2
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COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl.CS(=O)(=O)O
P234
1S/C21H19ClN4O4.CH4O3S/c1-29-1 ...... 27)(H2,25,26,28);1H3,(H,2,3,4)
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HWLFIUUAYLEFCT-UHFFFAOYSA-N
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100.243.376
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C₂₂H₂₃ClN₄O₇S
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DTXSID90235081
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P592
CHEMBL2105704
P652
3J78384F61