about
Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.Inhibition of Cycloartenol Synthase (CAS) Function in Tobacco BY-2 Cell Suspensions: A Proteomic Analysis.Inhibition of Cycloartenol Synthase (CAS) Function in Tobacco BY-2 Cells.The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.Cholesterol synthesis inhibitor RO 48-8071 suppresses transcriptional activity of human estrogen and androgen receptor.Cholesterol biosynthesis inhibitors as potent novel anti-cancer agents: suppression of hormone-dependent breast cancer by the oxidosqualene cyclase inhibitor RO 48-8071.
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Ro 48-8071 fumarate
@en
type
label
Ro 48-8071 fumarate
@en
prefLabel
Ro 48-8071 fumarate
@en
P592
P661
P662
P683
P1579
P2017
CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O
P2067
P231
189197-69-1
P233
CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=CC(=O)O)C(=O)O
P234
1S/C23H27BrFNO2.C4H4O4/c1-3-14 ...... 2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
P235
XCYAYLWZCRGKDS-WLHGVMLRSA-N
P274
C₂₇H₃₁BrFNO₆
P592
CHEMBL324162