Modulation of the maladaptive stress response to manage diseases of protein folding
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Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin DeficiencyCFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisRole of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative DiseasesRibosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression DefectTransportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1The biology of proteostasis in aging and disease.Blue journal conference. Aging and susceptibility to lung disease.The aggregation-prone intracellular serpin SRP-2 fails to transit the ER in Caenorhabditis elegans.The unpredictability of prolonged activation of stress response pathways.A Differentiation Transcription Factor Establishes Muscle-Specific Proteostasis in Caenorhabditis elegans.Hallmarks of therapeutic management of the cystic fibrosis functional landscape.Unravelling druggable signalling networks that control F508del-CFTR proteostasisProtein aggregation activates erratic stress response in dietary restricted yeast cells.Proteotoxicity and cardiac dysfunction.Targeting the PI3K/Akt/mTOR signalling pathway in Cystic FibrosisAging and Lung Disease. Clinical Impact and Cellular and Molecular Pathways.Correctors Rescue CFTR Mutations in Nucleotide-Binding Domain 1 (NBD1) by Modulating Proteostasis.HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models.Activation of heat shock response augments fibroblast growth factor-1 expression in wounded lung epithelium.Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.SYVN1, NEDD8, and FBXO2 Proteins Regulate ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation.Pathways of cellular proteostasis in aging and disease.α1-Antitrypsin deficiency.Failure of RQC machinery causes protein aggregation and proteotoxic stress.Oxidative and endoplasmic reticulum stress in respiratory disease.Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons.
P2860
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P2860
Modulation of the maladaptive stress response to manage diseases of protein folding
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Modulation of the maladaptive stress response to manage diseases of protein folding
@ast
Modulation of the maladaptive stress response to manage diseases of protein folding
@en
Modulation of the maladaptive stress response to manage diseases of protein folding
@nl
type
label
Modulation of the maladaptive stress response to manage diseases of protein folding
@ast
Modulation of the maladaptive stress response to manage diseases of protein folding
@en
Modulation of the maladaptive stress response to manage diseases of protein folding
@nl
prefLabel
Modulation of the maladaptive stress response to manage diseases of protein folding
@ast
Modulation of the maladaptive stress response to manage diseases of protein folding
@en
Modulation of the maladaptive stress response to manage diseases of protein folding
@nl
P2093
P2860
P3181
P1433
P1476
Modulation of the maladaptive stress response to manage diseases of protein folding
@en
P2093
Daniela Martino Roth
Darren M Hutt
Jeffrey M Beekman
Jiansong Tong
Johanna F Dekkers
Lawrence Drew
Marion Bouchecareilh
Richard I Morimoto
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001998
P407
P577
2014-11-01T00:00:00Z