Exacerbated innate host response to SARS-CoV in aged non-human primates
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Molecular pathology of emerging coronavirus infectionsCoronavirus virulence genes with main focus on SARS-CoV envelope geneViral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemicA mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variantIncreased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus.Advances in antivirals for non-influenza respiratory virus infections.Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence.Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaquesThe PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice.Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse modelEpithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques.Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates.Protein-Protein Interactions of Viroporins in Coronaviruses and Paramyxoviruses: New Targets for Antivirals?Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection.Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections.A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease.Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.A review of genetic methods and models for analysis of coronavirus-induced severe pneumonitis.Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo.Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ culturesInnate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirusMiddle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaquesThe replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokinesInhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survivalProtective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice.Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses.Animal models in virus research: their utility and limitations.Pathogenesis of Middle East respiratory syndrome coronavirus.Middle East respiratory syndrome and severe acute respiratory syndrome.Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology.MERS-coronavirus: From discovery to intervention.Recent developments in anti-severe acute respiratory syndrome coronavirus chemotherapyDistinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species.MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.
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P2860
Exacerbated innate host response to SARS-CoV in aged non-human primates
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Exacerbated innate host response to SARS-CoV in aged non-human primates
@ast
Exacerbated innate host response to SARS-CoV in aged non-human primates
@en
Exacerbated innate host response to SARS-CoV in aged non-human primates
@nl
type
label
Exacerbated innate host response to SARS-CoV in aged non-human primates
@ast
Exacerbated innate host response to SARS-CoV in aged non-human primates
@en
Exacerbated innate host response to SARS-CoV in aged non-human primates
@nl
prefLabel
Exacerbated innate host response to SARS-CoV in aged non-human primates
@ast
Exacerbated innate host response to SARS-CoV in aged non-human primates
@en
Exacerbated innate host response to SARS-CoV in aged non-human primates
@nl
P2093
P2860
P50
P1433
P1476
Exacerbated innate host response to SARS-CoV in aged non-human primates
@en
P2093
Anna de Lang
Arno C Andeweg
Geert van Amerongen
Judith M A van den Brand
Lonneke M Leijten
Marinus J C Eijkemans
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000756
P407
P577
2010-02-01T00:00:00Z