Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's DiseaseHow Do Meningeal Lymphatic Vessels Drain the CNS?Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice.Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD MouseLRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric StateLow-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis.Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative DisordersInhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.LRP in Endothelial Cells: A Little Goes a Long Way.Vascular and Metabolic Factors in Alzheimer's Disease and Related Dementias: IntroductionAlpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine.Understanding the functions and relationships of the glymphatic system and meningeal lymphatics.Metabolite Clearance During Wakefulness and Sleep.Altered Met Receptor Phosphorylation and LRP1 Mediated Uptake in Cells Lacking Carbohydrate-Dependent Lysosomal Targeting.The effect of aging on brain barriers and the consequences for Alzheimer's disease development.Re-engineering therapeutic antibodies for Alzheimer's disease as blood-brain barrier penetrating bi-specific antibodies.The blood-brain barrier in Alzheimer's disease.Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease.Sex Hormone Decline and Amyloid β Synthesis, Transport and Clearance in the Brain.Phytosterols and Dementia.Barrier function in the peripheral and central nervous system-a review.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease.Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before: ApoE, APP transcription and AD: Hypothesised mechanisms and existing knowledge gaps.Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets.Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer's Disease.Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta.Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptideAlzheimer's disease: A matter of blood-brain barrier dysfunction?Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity.Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model.Neuroprotective effect of formononetin in ameliorating learning and memory impairment in mouse model of Alzheimer's disease.Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice.Blood-derived amyloid-β protein induces Alzheimer's disease pathologies.Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders.Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.
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P2860
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
description
2015 nî lūn-bûn
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2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@ast
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@en
Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
@nl
type
label
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@ast
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@en
Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
@nl
prefLabel
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@ast
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@en
Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier
@en
P2093
Carsten Korth
Claus U Pietrzik
Ingrid Prikulis
Julius N Meißner
Julius Nahrath
Nils Schubert
Sabrina Meister
Sandra Baches
Sascha Weggen
Thomas A Bayer
P2860
P304
P3181
P356
10.1172/JCI81108
P407
P577
2015-11-30T00:00:00Z