Coagulation factor X activates innate immunity to human species C adenovirus - sprookjes - yvandenbroek - TriplyDB

Coagulation factor X activates innate immunity to human species C adenovirus

Coagulation factor X activates innate immunity to human species C adenovirus

http://www.wikidata.org/entity/Q27332110

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Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5-based Constructs Adenovirus vectors for gene therapy, vaccination and cancer gene therapy An intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5 CryoEM and Molecular Dynamics of the Circadian KaiB–KaiC Complex Indicates That KaiB Monomers Interact with KaiC and Block ATP Binding Clefts Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model.Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancer Immune tolerance induction to factor IX through B cell gene transfer: TLR9 signaling delineates between tolerogenic and immunogenic B cells.Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus.Immune responses to human factor IX in haemophilia B mice of different genetic backgrounds are distinct and modified by TLR4.IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells A hybrid computational method for the discovery of novel reproduction-related genes.Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups.Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.Differential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs. adeno-associated viral vectors in vivo.The relevance of coagulation factor X protection of adenoviruses in human sera.Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy.A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism Retargeting of gene expression using endothelium specific hexon modified adenoviral vector.Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43.Innate immunity to adenovirus.Human full-length coagulation factor X and a GLA domain-derived 40-mer polypeptide bind to different regions of the adenovirus serotype 5 hexon capsomer.Multiple roles of the coagulation protease cascade during virus infection.The procoagulant envelope virus surface: contribution to enhanced infection.The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery.Pre-existing immunity against Ad vectors: humoral, cellular, and innate response, what's important?.TANK-binding kinase 1-dependent or -independent signaling elicits the cell-type-specific innate immune responses induced by the adenovirus vector.The inflammatory actions of coagulant and fibrinolytic proteases in disease.Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum.Adenovirus sensing by the immune system.Oncolytic adenoviruses: design, generation, and experimental procedures.Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages.Evaluating the Impact of Natural IgM on Adenovirus Type 5 Gene Therapy Vectors.Coagulation factor binding orientation and dimerization may influence infectivity of adenovirus-coagulation factor complexes.

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Coagulation factor X activates innate immunity to human species C adenovirus

http://www.wikidata.org/entity/Q27332110

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Coagulation factor X activates innate immunity to human species C adenovirus

@ast

Coagulation factor X activates innate immunity to human species C adenovirus

@en

Coagulation factor X activates innate immunity to human species C adenovirus

@nl

type

label

Coagulation factor X activates innate immunity to human species C adenovirus

@ast

Coagulation factor X activates innate immunity to human species C adenovirus

@en

Coagulation factor X activates innate immunity to human species C adenovirus

@nl

prefLabel

Coagulation factor X activates innate immunity to human species C adenovirus

@ast

Coagulation factor X activates innate immunity to human species C adenovirus

@en

Coagulation factor X activates innate immunity to human species C adenovirus

@nl

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Coagulation factor X activates innate immunity to human species C adenovirus

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Frederico M Farin

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James W MacDonald

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John P Sumida

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Kensuke Miyake

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Konstantin Doronin

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Mauro Acchione

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Nelson C Di Paolo

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Oleksandr Kalyuzhniy

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Phoebe L Stewart

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Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

The danger model: a renewed sense of self

Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics.

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

Empirical array quality weights in the analysis of microarray data

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons.

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