An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
about
Evidence that SOX2 overexpression is oncogenic in the lungDisruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancerHdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cellsRegulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinomaLimbal stem cell transplantation: current perspectivesPalatogenesis and cutaneous repair: A two-headed coindeltaNp63 has a role in maintaining epithelial integrity in airway epitheliumRole of epidermal primary cilia in the homeostasis of skin and hair folliclesForward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cellsΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiationDysregulated ΔNp63α inhibits expression of Ink4a/arf, blocks senescence, and promotes malignant conversion of keratinocytesThe WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineageIdentification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics.Reduction of collagen VII anchoring fibrils in the airway basement membrane zone of infant rhesus monkeys exposed to house dust miteAbnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha.p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.p53/p63/p73 in the epidermis in health and diseasep63 in skin development and ectodermal dysplasias.p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiationβ-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.Essential roles of androgen signaling in Wolffian duct stabilization and epididymal cell differentiationEzh2 represses the basal cell lineage during lung endoderm development.DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epitheliumWnt and FGF mediated epithelial-mesenchymal crosstalk during lung development.Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas.p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.p53 Family: Role of Protein Isoforms in Human Cancer.BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin.Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytesPathway Regulation of p63, a Director of Epithelial Cell FateA global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues.ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion.ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammationRole of p63 in Development, Tumorigenesis and Cancer ProgressionVimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients.The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.Brg1 determines urothelial cell fate during ureter developmentA/T gap tolerance in the core sequence and flanking sequence requirements of non-canonical p53 response elements
P2860
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P2860
An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An active role of the DeltaN i ...... directing epidermal cell fate
@ast
An active role of the DeltaN i ...... directing epidermal cell fate
@en
An active role of the DeltaN i ...... directing epidermal cell fate
@nl
type
label
An active role of the DeltaN i ...... directing epidermal cell fate
@ast
An active role of the DeltaN i ...... directing epidermal cell fate
@en
An active role of the DeltaN i ...... directing epidermal cell fate
@nl
prefLabel
An active role of the DeltaN i ...... directing epidermal cell fate
@ast
An active role of the DeltaN i ...... directing epidermal cell fate
@en
An active role of the DeltaN i ...... directing epidermal cell fate
@nl
P2093
P2860
P3181
P1433
P1476
An active role of the DeltaN i ...... directing epidermal cell fate
@en
P2093
Barbara Birkaya
Kirsten Smalley
Rose-Anne Romano
Satrajit Sinha
P2860
P3181
P356
10.1371/JOURNAL.PONE.0005623
P407
P577
2009-01-01T00:00:00Z