Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase
about
Viral hepatitis and hepatocellular carcinomaIntracellular events and cell fate in filovirus infectionLatently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase.Antiviral actions of interferonsRubella virus replication and links to teratogenicityAlpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replicationImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionGenetic heterogeneity of hypervariable region 1 of the hepatitis C virus (HCV) genome and sensitivity of HCV to alpha interferon therapy.Noncytopathic Bovine Viral Diarrhea Virus Inhibits Double-Stranded RNA-Induced Apoptosis and Interferon SynthesisHepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response.Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5AInduced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1Regulation of PKR and IRF-1 during hepatitis C virus RNA replication.Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells.Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-KinasePKR-dependent mechanisms of gene expression from a subgenomic hepatitis C virus clone.Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNAPKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in NeuronsGene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A ProteinAn 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cellsReplicative Homeostasis III: implications for antiviral therapy and mechanisms of response and non-responseA transgenic mouse model of steatosis and hepatocellular carcinoma associated with chronic hepatitis C virus infection in humansAcute hepatitis C virus infection: A chronic problemMutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of Hepatitis C Virus Genotype 1 and Their Relationships to Pegylated Interferon-Ribavirin Treatment ResponsesInteraction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus ParticlesThe hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivoHepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R.Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor.Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent mannerMutations in carboxy-terminal part of E2 including PKR/eIF2alpha phosphorylation homology domain and interferon sensitivity determining region of nonstructural 5A of hepatitis C virus 1b: their correlation with response to interferon monotherapy andHepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection.Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.Translational control of viral gene expression in eukaryotesHCV genome-wide genetic analyses in context of disease progression and hepatocellular carcinoma.Regulation of PKR by HCV IRES RNA: importance of domain II and NS5AHeat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication.Recent insights on risk factors of hepatocellular carcinomaHepatitis C virus NS5A inhibitors and drug resistance mutations.The effect of IFNgamma on the hepatocyte: cell cycle and apoptosis.Evaluating the impact of hepatitis C virus (HCV) on highly active antiretroviral therapy-mediated immune responses in HCV/HIV-coinfected women: role of HCV on expression of primed/memory T cells
P2860
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P2860
Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@ast
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@en
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@nl
type
label
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@ast
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@en
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@nl
prefLabel
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@ast
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@en
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@nl
P2093
P2860
P1433
P1476
Antiapoptotic and oncogenic po ...... sion of the PKR protein kinase
@en
P2093
P2860
P304
P577
1999-08-01T00:00:00Z