Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
about
The hepatitis C virus glycan shield and evasion of the humoral immune responseNeutralizing antibody response to hepatitis C virusPreclinical Evaluation of Two Neutralizing Human Monoclonal Antibodies against Hepatitis C Virus (HCV): a Potential Treatment To Prevent HCV Reinfection in Liver Transplant PatientsImmunogenic and Functional Organization of Hepatitis C Virus (HCV) Glycoprotein E2 on Infectious HCV VirionsThe Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope ProteinExpression and Characterization of a Minimal Hepatitis C Virus Glycoprotein E2 Core Domain That Retains CD81 BindingStudying Hepatitis C Virus: Making the Best of a Bad VirusHuman combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virusIsolation and Characterization of Broadly Neutralizing Human Monoclonal Antibodies to the E1 Glycoprotein of Hepatitis C VirusStructural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 envelope glycoproteinA Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational EpitopeDefinition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal AntibodiesIn vitro selection of a neutralization-resistant hepatitis C virus escape mutantMutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus InfectivityProduction of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing MutationsLow pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus ParticlesStructure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolateCapitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine designAdaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors.Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis C virus E2 glycoprotein encompassing amino acids 412-423Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus.Hepatitis C virus is primed by CD81 protein for low pH-dependent fusionMapping a region of hepatitis C virus E2 that is responsible for escape from neutralizing antibodies and a core CD81-binding region that does not tolerate neutralization escape mutations.Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody.Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoproteinBroad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV InfectionRecent advances in our understanding of receptor binding, viral fusion and cell entry of hepatitis C virus: new targets for the design of antiviral agents.Immunogenicity and functional characterization of Leishmania-derived hepatitis C virus envelope glycoprotein complex.Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design.Adaptive immunity to the hepatitis C virus.The past, present and future of neutralizing antibodies for hepatitis C virus.An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry.Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies.Viral evasion and challenges of hepatitis C virus vaccine development.Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus.
P2860
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P2860
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
description
2005 nî lūn-bûn
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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@ast
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@en
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@nl
type
label
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@ast
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@en
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@nl
prefLabel
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@ast
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@en
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@nl
P2093
P2860
P50
P3181
P1433
P1476
Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2
@en
P2093
Jinming Xia
Steven K H Foung
Zhen-Yong Keck
P2860
P304
P3181
P356
10.1128/JVI.79.21.13199-13208.2005
P577
2005-11-01T00:00:00Z