Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model
about
Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase betaHepatitis C virus core protein is a dimeric alpha-helical protein exhibiting membrane protein features.Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocytesHepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune ResponsesHepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cellsApoptosis in animal models of virus-induced diseaseIncreased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation.Expression of hepatitis C virus core protein in hepatocytes does not modulate proliferation or apoptosis of CD8+ T cells.Production and pathogenicity of hepatitis C virus core gene products.The wild-type hepatitis C virus core inhibits initiation of antigen-specific T- and B-cell immune responses in BALB/c miceInhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo.Generation of the regulatory protein rtTA transgenic mice.Transcriptional repression of C4 complement by hepatitis C virus proteins.Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and -8 expression on peripheral CD4+ and CD8+ T-cells.Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling.Viral modulation of T-cell receptor signalingNew animal models for hepatitis C viral infection and pathogenesis studies.Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular CarcinomaCD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells.Dendritic cells in hepatitis C infection: can they (help) win the battle?Animal models in the study of hepatitis C virus-associated liver pathologies.Advances in hepatitis C virus vaccines, Part one: Advances in basic knowledge for hepatitis C virus vaccine design.Leptin receptor isoforms mRNA expression in peripheral blood mononuclear cells from patients with chronic viral hepatitis.Immune modulation by the hepatitis C virus core protein.Memory T-cell-mediated immune responses specific to an alternative core protein in hepatitis C virus infection.Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses.F protein increases CD4+CD25+ T cell population in patients with chronic hepatitis C.Schistosoma infection inhibits cellular immune responses to core HCV peptides.Influence of human T-lymphotropic virus type 1 coinfection on the development of hepatocellular carcinoma in patients with hepatitis C virus infection.Modulation of Cell Death Pathways by Hepatitis C Virus Proteins in Huh7.5 Hepatoma Cells.Prevalence and etiology of elevated serum alanine aminotransferase level in an adult population in Taiwan.
P2860
Q27469813-31C2DF57-EC5B-45C3-A8E8-5FFBCAEC3B78Q27470776-3FE462ED-A4CA-4E3D-B5AB-BF4D79578B69Q27473390-80660582-28DD-44F0-A590-5B084EC899BAQ27485419-9B2D8B8A-48F6-4EC8-9CF3-58AAF183ADF5Q27488899-5FF7371A-0167-467B-A17C-FFF45ECAF8B7Q27490338-34FC264D-A087-416C-9C18-C66163EE064AQ30436833-E372B2BC-6CCC-4F9E-886E-9FF152AB9949Q33607229-7685C788-97B1-47C2-A566-9F0DF8B0D298Q33780095-A5F5B44D-EB26-4A88-B49E-2E02DF28647EQ33962697-D8753EDA-EB4C-4210-90F4-2D2F4B910236Q34425267-8D02AD59-AF2E-4A7E-B32C-5F4696E86009Q35010274-E2209F6B-7385-4550-AE7E-B57340F0AA36Q35076923-A646C865-CC15-42D6-80D9-F76AC7A6CD5DQ35154403-75B5B378-272F-447F-8FA6-C88425552E15Q36257528-0A586D34-B1F1-4E4A-A7A8-98D952B74CDAQ36540182-ABE5B3D4-79D1-4406-A992-6F06F25BC6C1Q36841728-CCF90D42-9F7D-4257-B893-51F85051A4CCQ37297666-59A2B254-B0E2-495B-BE68-7E48E812E8E7Q37495787-0AEEECBC-BD2C-4F4A-A5F1-23C8D2E46E1FQ37843841-3E8667FF-7413-45E5-BD41-F5C36D2F661FQ37886159-3F0544B7-9FE5-4560-8A49-BC34E36BD5BEQ37948856-AE546BBB-E010-46D5-93D4-31AE6D243D96Q38308234-01DADE1A-BB99-4BA9-B3BF-F314EE42B9F7Q39090584-E92C46EA-E787-44E7-8400-8CE1FB8D2E8DQ39991596-FD19F22A-A46F-4B42-A1C0-93A4F72060ECQ40976402-535B9F3F-A552-462E-9572-6B02D1EB1F84Q41344021-044CD225-6E22-4717-ACBC-8D0FAAA805A7Q41899846-E8372CA4-410C-417F-BA25-0B6A00C9ADE5Q42241090-6F5524CD-4AE7-4813-86B2-3CBA7B31F57BQ45325177-C1B8021F-E95A-453C-95F7-DC6BEAC2F273Q51465087-4FA943EB-1525-4CB4-8468-C11D96E41B73
P2860
Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Hepatitis C Virus Core Protein ...... e in a Transgenic Murine Model
@nl
Hepatitis C virus core protein ...... e in a transgenic murine model
@ast
Hepatitis C virus core protein ...... e in a transgenic murine model
@en
type
label
Hepatitis C Virus Core Protein ...... e in a Transgenic Murine Model
@nl
Hepatitis C virus core protein ...... e in a transgenic murine model
@ast
Hepatitis C virus core protein ...... e in a transgenic murine model
@en
prefLabel
Hepatitis C Virus Core Protein ...... e in a Transgenic Murine Model
@nl
Hepatitis C virus core protein ...... e in a transgenic murine model
@ast
Hepatitis C virus core protein ...... e in a transgenic murine model
@en
P2093
P2860
P1433
P1476
Hepatitis C virus core protein ...... e in a transgenic murine model
@en
P2093
Carolina Soguero
Duong Tony Nguyen
Kenneth Tung
Myungsoo Joo
Young S Hahn
P2860
P304
P356
10.1128/JVI.76.18.9345-9354.2002
P577
2002-09-01T00:00:00Z