Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells - sprookjes - yvandenbroek - TriplyDB

Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

http://www.wikidata.org/entity/Q27473340

about

New hepatitis C virus drug discovery strategies and model systems Development of a cell-based high-throughput specificity screen using a hepatitis C virus-bovine viral diarrhea virus dual replicon assay.Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system.Effect of cell growth on hepatitis C virus (HCV) replication and a mechanism of cell confluence-based inhibition of HCV RNA and protein expression Novel Robust Hepatitis C Virus Mouse Efficacy Model Replication and IRES-Dependent Translation Are Both Affected by Core Coding Sequences in Subgenomic GB Virus B Replicons Superinfection Exclusion in Cells Infected with Hepatitis C Virus Hep3B Human Hepatoma Cells Support Replication of the Wild-Type and a 5'-End Deletion Mutant GB Virus B Replicon Selection of an optimal RNA transfection reagent and comparison to electroporation for the delivery of viral RNA Hepatitis C virus replicons: dinosaurs still in business?Development of a Cell-Based Hepatitis C Virus Infection Fluorescent Resonance Energy Transfer Assay for High-Throughput Antiviral Compound Screening Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening.Evaluation of compound activity against hepatitis C virus in replicon systems.Hepatitis C virus experimental model systems and antiviral drug research.Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV.Survivin-targeting Artificial MicroRNAs Mediated by Adenovirus Suppress Tumor Activity in Cancer Cells and Xenograft Models Hepatitis C drug discovery: in vitro and in vivo systems and drugs in the pipeline.Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus.Recent contributions of in vitro models to our understanding of hepatitis C virus life cycle.Conventional protein kinase C inhibition prevents alpha interferon-mediated hepatitis C virus replicon clearance by impairing STAT activation Tricistronic hepatitis C virus subgenomic replicon expressing double transgenes.Novel hepatitis C virus reporter replicon cell lines enable efficient antiviral screening against genotype 1a Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture.Hepatitis C virus subgenomic replicons in the human embryonic kidney 293 cell line.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro.Effect of interaction between hepatitis C virus NS5A and NS5B on hepatitis C virus RNA replication with the hepatitis C virus replicon.Ralf Bartenschlager, Charles Rice, and Michael Sofia are honored with the 2016 Lasker~DeBakey Clinical Medical Research Award.An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA.Identification of a key determinant of hepatitis C virus cell culture adaptation in domain II of NS3 helicase.Subgenomic HCV RNA replication and its localization in the nucleus of the infected cells.Engineered Livers for Infectious Diseases.Hepatitis C virus: Morphogenesis, infection and therapy.

P2860

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P2860

Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

http://www.wikidata.org/entity/Q27473340

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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P356

JVI.77.5.2928-2935.2003

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Journal of Virology

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Persistent Replication of Hepa ...... f Highly Permissive Huh7 Cells

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P2093

Adam J Simon

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Edward M Murray

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Eric J Markel

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Giacomo Paonessa

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Jay A Grobler

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Marco F Pagnoni

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Osvaldo A Flores

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P2860

Characterization of cell lines carrying self-replicating hepatitis C virus RNAs.

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.

Effect of alpha interferon on the hepatitis C virus replicon

Regulation of PKR and IRF-1 during hepatitis C virus RNA replication.

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells.

Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA

Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism

Internal ribosome entry site within hepatitis C virus RNA

Efficient initiation of HCV RNA replication in cell culture

P304

2928-35

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10.1128/JVI.77.5.2928-2935.2003

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5

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77

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2003-03-01T00:00:00Z

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12584317

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149762

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