Chimeric alphavirus vaccine candidates for chikungunya - sprookjes - yvandenbroek - TriplyDB

Chimeric alphavirus vaccine candidates for chikungunya

Chimeric alphavirus vaccine candidates for chikungunya

http://www.wikidata.org/entity/Q27487105

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Antiviral perspectives for chikungunya virus Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism Production of Chikungunya Virus-Like Particles and Subunit Vaccines in Insect Cells Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection DNA vaccine initiates replication of live attenuated chikungunya virus in vitro and elicits protective immune response in mice Prime-boost immunization strategies against Chikungunya virus Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection Dissecting the Role of E2 Protein Domains in Alphavirus Pathogenicity Antiviral Hammerhead Ribozymes Are Effective for Developing Transgenic Suppression of Chikungunya Virus in Aedes aegypti Mosquitoes Chikungunya vaccines in development The Global Virus Network: Challenging chikungunya Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus A nonhuman primate model of chikungunya disease Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies.Development of Vaccines for Chikungunya Fever.Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines.Next generation sequencing of DNA-launched Chikungunya vaccine virus.Chikungunya: a potentially emerging epidemic?A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates A small antigenic determinant of the Chikungunya virus E2 protein is sufficient to induce neutralizing antibodies which are partially protective in mice Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose.Neurocognitive outcome of children exposed to perinatal mother-to-child Chikungunya virus infection: the CHIMERE cohort study on Reunion Island.Chikungunya virus arthritis in adult wild-type mice.Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein.Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.Effective chikungunya virus-like particle vaccine produced in insect cells.Stability of RNA virus attenuation approaches A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis Biodefense Oriented Genomic-Based Pathogen Classification Systems: Challenges and Opportunities.Venezuelan equine encephalitis virus variants lacking transcription inhibitory functions demonstrate highly attenuated phenotype.Transmission potential of two chimeric Chikungunya vaccine candidates in the urban mosquito vectors, Aedes aegypti and Ae. albopictus.Design of chimeric alphaviruses with a programmed, attenuated, cell type-restricted phenotype.Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design Conservation of a packaging signal and the viral genome RNA packaging mechanism in alphavirus evolution.Enhanced production of Chikungunya virus-like particles using a high-pH adapted spodoptera frugiperda insect cell line.Chimeric Chikungunya viruses are nonpathogenic in highly sensitive mouse models but efficiently induce a protective immune response.Chikungunya virus: evolution and genetic determinants of emergence.

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Chimeric alphavirus vaccine candidates for chikungunya

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2008年論文

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2008年論文

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J.VACCINE.2008.07.054

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Chimeric alphavirus vaccine candidates for chikungunya

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A Paige Adams

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Eugenia Volkova

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Naomi Forrester

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Shu-Yuan Xiao

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Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

Chikungunya and dengue: a case of mistaken identity?

Large-plaque mutants of Sindbis virus show reduced binding to heparan sulfate, heightened viremia, and slower clearance from the circulation

Capsid Protein of Eastern Equine Encephalitis Virus Inhibits Host Cell Gene Expression

Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice

Structural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine Virulence

Attenuation of Venezuelan equine encephalitis virus strain TC-83 is encoded by the 5'-noncoding region and the E2 envelope glycoprotein

Common Marmosets (Callithrix jacchus) as a Nonhuman Primate Model To Assess the Virulence of Eastern Equine Encephalitis Virus Strains

Increased Mortality Rate Associated with Chikungunya Epidemic, Ahmedabad, India

Infection with chikungunya virus in Italy: an outbreak in a temperate region

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Scott C. Weaver

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23160785

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Chikungunya virus

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2571998

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