Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold
about
The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent mannerMechanism-based inhibition of the melatonin rhythm enzyme: pharmacologic exploitation of active site functional plasticityEvolution of a microbial nitrilase gene family: a comparative and environmental genomics study.Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Bacterial GCN5-Related N-Acetyltransferases: From Resistance to RegulationStrategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infectionsThe crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferaseSubstrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily membersStructure of the bacillus subtilis YYCN protein: a putative N-acetyltransferaseThe molecular basis of glyphosate resistance by an optimized microbial acetyltransferaseEnzyme structural plasticity and the emergence of broad-spectrum antibiotic resistanceRifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of ArrStructure of a putative acetyltransferase (PA1377) fromPseudomonas aeruginosaEvolution of insect arylalkylamine N-acetyltransferases: Structural evidence from the yellow fever mosquito, Aedes aegyptiCrystal structure of Mycobacterium tuberculosis Rv3168: a putative aminoglycoside antibiotics resistance enzymeInhibition of aminoglycoside-deactivating enzymes APH(3')-IIIa and AAC(6')-Ii by amphiphilic paromomycin O2''-ether analoguesStructural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolismCrystal structure of the dopamine N -acetyltransferase–acetyl-CoA complex provides insights into the catalytic mechanismAminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistanceBroad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificityStructural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferaseA novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium.Uncultured soil bacteria are a reservoir of new antibiotic resistance genes.Mutagenesis analysis of a conserved region involved in acetyl coenzyme A binding in the aminoglycoside 6'-N-acetyltransferase type Ib encoded by plasmid pJHCMW1.Effects of F171 mutations in the 6'-N-acetyltransferase type Ib [AAC(6')-Ib] enzyme on susceptibility to aminoglycosides.Systematic analysis of a conserved region of the aminoglycoside 6'-N-acetyltransferase type Ib.Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysis.Aminoglycoside modifying enzymes.Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis.Synthesis of a phosphonate-linked aminoglycoside-coenzyme a bisubstrate and use in mechanistic studies of an enzyme involved in aminoglycoside resistanceSynthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside-CoA bisubstrates as mechanistic probes for aminoglycoside N-6'-acetyltransferase.Synthesis of 4'-aminopantetheine and derivatives to probe aminoglycoside N-6'-acetyltransferaseStructural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT(2″)-IaCollecting variable-concentration isothermal titration calorimetry datasets in order to determine binding mechanismsThe aminoglycoside 6'-N-acetyltransferase type Ib encoded by Tn1331 is evenly distributed within the cell's cytoplasm.Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophilaCosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosisRise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm.Solution NMR Spectroscopy for the Study of Enzyme Allostery.
P2860
Q24305568-293E547E-8955-4389-8A63-459BFC94957BQ24655023-3E9BA0C6-6113-4850-BE71-15382E8DCB88Q24811393-09DC2713-7508-44B6-A5D4-979AACA07A04Q26314426-6A27CC94-10BD-4F1F-939F-5B99F7DD53D2Q26773344-F0F303FE-859C-4482-A0C8-390BFBFA3D4BQ26859978-0908FE8F-B55C-4D08-B5DA-5B04035171D2Q27630892-BD26F18D-C7CA-4DC5-8F29-47FE99BADE03Q27638972-8CEC792D-A16A-4678-8CA6-67328441EEDEQ27640518-A29EA9FB-DB46-4CD2-81FA-433267B3521FQ27642616-4CB0A7D3-251E-4D57-BDC4-6A6203F3C737Q27643715-4B1FEDD1-F606-44A5-9755-B9934644BF8FQ27649912-7118E8E8-0000-47EA-A08F-722A26E6FBD5Q27650104-A00BB2AA-4B45-4F09-A5BA-DCE4A05ECB13Q27650515-74DA83BA-D27E-4D16-8359-143ED1567078Q27670611-2368D19C-A11E-4986-A24C-6BF828E19922Q27673650-1F9D4E32-AEE6-4349-B6F4-2C32D225F4D7Q27673672-153F6B29-A572-4710-BBCE-564E276312B2Q27678873-FE4BCCDB-4A20-4BBD-B5F6-DB1F93E30A6AQ27681264-04FF96E8-98AB-425B-9B17-7EAD745881EFQ28138065-C7CB517A-45BA-43FF-A3EA-99B34EF089CCQ28485785-164B7FE6-B833-45AB-81A2-126C1B560151Q28488939-22A3AFE4-33AD-4C71-9E6B-B516AC55AE48Q31158535-EAF68582-B250-4D4B-84DC-62669FE4B4D1Q33205796-A2A5C960-AABE-4D5A-9FCF-FB17098311CDQ33883705-D05AB245-24DF-4BDF-AECB-EF176E52ABF3Q33978164-E9A16720-7EE6-4468-BAD2-D7CE529747B0Q33983481-D6BE473E-3154-4997-90BC-DB8D489E2D42Q34299292-FFD54C17-B257-4372-BDEA-9A3A3BE95ECCQ34354185-98464CC3-8DFA-45E9-95D1-271EE1E5B8DEQ34549307-F8A84CD1-7918-464C-920E-7C5492F22CC0Q34881953-897CA4B1-081A-46B0-8B05-23147F02B675Q34882015-80D1C145-2841-46CD-A4F7-27DCCFB2B6F4Q34882031-3B86F7BA-F434-4B27-97F1-88A46CF87BF6Q35038252-7359E2E5-899F-4610-8D5A-A00232614F70Q35203121-CF5986B5-B91A-4BA7-BF2B-C22C5224E2E6Q35685247-7FB3F4C8-4BF2-41DB-A003-6D09BB11E981Q35950741-AA0B160E-4A19-4240-88F0-6AFA2EE2649BQ36364084-5B02480F-768E-403E-8588-E78F622AE60BQ36850490-F0C0ABC1-87EA-44F0-8904-1533A1FAA5EBQ37076848-9F3D3CB5-3DA7-42A5-BA49-C0DE752B45C2
P2860
Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of an aminog ...... yltransferase superfamily fold
@ast
Crystal structure of an aminog ...... yltransferase superfamily fold
@en
Crystal structure of an aminog ...... yltransferase superfamily fold
@nl
type
label
Crystal structure of an aminog ...... yltransferase superfamily fold
@ast
Crystal structure of an aminog ...... yltransferase superfamily fold
@en
Crystal structure of an aminog ...... yltransferase superfamily fold
@nl
prefLabel
Crystal structure of an aminog ...... yltransferase superfamily fold
@ast
Crystal structure of an aminog ...... yltransferase superfamily fold
@en
Crystal structure of an aminog ...... yltransferase superfamily fold
@nl
P2093
P3181
P1433
P1476
Crystal structure of an aminog ...... yltransferase superfamily fold
@en
P2093
A M Berghuis
L E Wybenga-Groot
P304
P3181
P356
10.1016/S0969-2126(99)80066-5
P577
1999-05-01T00:00:00Z