Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
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RBM4 interacts with an intronic element and stimulates tau exon 10 inclusionRNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice siteA unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptorA conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architectureEvidence that RNA editing modulates splice site selection in the 5-HT2C receptor geneITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysmsRole of RNA structure in regulating pre-mRNA splicingFunctional MAPT haplotypes: bridging the gap between genotype and neuropathologySplicing in action: assessing disease causing sequence changesThe reduced expression of the HADH2 protein causes X-linked mental retardation, choreoathetosis, and abnormal behaviorAntisense-mediated exon skipping: a versatile tool with therapeutic and research applicationsFrontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutationsThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetInvited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimagingStructural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)Targeting mRNA for Alzheimer's and related dementias.Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's diseaseExpression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brainAmetantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.Tau filament formation in transgenic mice expressing P301L tau.Identification of tau stem loop RNA stabilizers.Transgenic models of tauopathies and synucleinopathies.Template-directed synthesis of a small molecule-antisense conjugate targeting an mRNA structure.Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau.PMD patient mutations reveal a long-distance intronic interaction that regulates PLP1/DM20 alternative splicing.Studying RNA using site-directed spin-labeling and continuous-wave electron paramagnetic resonance spectroscopySorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients.The cytoskeleton in neurodegenerative diseases.Contributions of stacking, preorganization, and hydrogen bonding to the thermodynamic stability of duplexes between RNA and 2'-O-methyl RNA with locked nucleic acids.Hereditary frontotemporal dementia caused by Tau gene mutations.Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR proteinThe role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.Association between GRIN3A gene polymorphism in Kawasaki disease and coronary artery aneurysms in Taiwanese children.Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.Global analysis of protein folding thermodynamics for disease state characterizationGenomic variants in exons and introns: identifying the splicing spoilers.Neurodegenerative tauopathy in the worm.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.
P2860
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P2860
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@ast
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@en
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@nl
type
label
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@ast
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@en
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@nl
prefLabel
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@ast
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@en
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@nl
P2093
P2860
P921
P356
P1476
Structure of tau exon 10 splic ...... sonism linked to chromosome 17
@en
P2093
J R Murrell
M G Spillantini
M Hasegawa
P2860
P304
P356
10.1073/PNAS.96.14.8229
P407
P577
1999-07-06T00:00:00Z