Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses
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Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitorsComputational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitorsStructure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors.Search for non-nucleoside inhibitors of HIV-1 reverse transcriptase using chemical similarity, molecular docking, and MM-GB/SA scoringE/Z Energetics for Molecular Modeling and DesignConformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding.The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.Human immunodeficiency virus type 2 reverse transcriptase activity in model systems that mimic steps in reverse transcription.Bifunctional inhibition of HIV-1 reverse transcriptase: a first step in designing a bifunctional triphosphate.C-2-aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors.A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]).Conformational restriction: an effective tactic in 'follow-on'-based drug discovery.In silico structure-based design of a potent, mutation resilient, small peptide inhibitor of HIV-1 reverse transcriptase.Mechanistic Study of Common Non-Nucleoside Reverse Transcriptase Inhibitor-Resistant Mutations with K103N and Y181C SubstitutionsNew thiourea and 1,3-thiazolidin-4-one derivatives effective on the HIV-1 virus.Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419.Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus.Synthesis, crystal structure, anti-HIV, and antiproliferative activity of new oxadiazole and thiazole analogsEfficacy and resistance of recently developed non-nucleoside reverse transcriptase inhibitors for HIV-1
P2860
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P2860
Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
@nl
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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P2093
P2860
P50
P3181
P356
P1476
Phenylethylthiazolylthiourea ( ...... tural and biochemical analyses
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P2093
D K Stammers
J Balzarini
R M Esnouf
P2860
P304
P3181
P356
10.1074/JBC.275.8.5633
P407
P577
2000-02-01T00:00:00Z