Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
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Mycobacterium tuberculosis CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGSDeterminants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACIDStructural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathwayCrystal Structures of Cytochrome P450 2B4 in Complex with the Inhibitor 1-Biphenyl-4-methyl-1 H -imidazole: Ligand-Induced Structural Response through α-Helical Repositioning ,Structural Evidence for Enhancement of Sequential Vitamin D3 Hydroxylation Activities by Directed Evolution of Cytochrome P450 Vitamin D3 HydroxylaseStructural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert -Butylphenylacetylene: Insight into Partial Enzymatic ActivityTargeted metagenomics: finding rare tryptophan dimer natural products in the environmentAllosteric transitions in cytochrome P450eryF explored with pressure-perturbation spectroscopy, lifetime FRET, and a novel fluorescent substrate, Fluorol-7GA.Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substatesNatural products version 2.0: connecting genes to molecules.Resolution of two substrate-binding sites in an engineered cytochrome P450eryF bearing a fluorescent probe.Multiple substrate-binding sites are retained in cytochrome P450 3A4 mutants with decreased cooperativity.Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsEnergetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions.Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomerThe use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4Substrate binding to cytochromes P450.The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.Cooperative properties of cytochromes P450.Conformational plasticity and structure/function relationships in cytochromes P450.Diversity of P450 enzymes in the biosynthesis of natural productsEvidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativityConformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.Indole hydroxylation by bacterial cytochrome P450 BM-3 and modulation of activity by cumene hydroperoxide.
P2860
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P2860
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@ast
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@en
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@nl
type
label
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@ast
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@en
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@nl
prefLabel
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@ast
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@en
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@nl
P2093
P2860
P356
P1476
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
@en
P2093
J Cupp-Vickery
R Anderson
Z Hatziris
P2860
P304
P356
10.1073/PNAS.050406897
P407
P577
2000-03-28T00:00:00Z