Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue
about
The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual featuresLeukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic acid binding proteinsCharacterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificityGranzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.IR laser-induced protein crystal transformation.Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric statesCytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.Delivery and therapeutic potential of human granzyme B.Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data.Death by a thousand cuts: granzyme pathways of programmed cell deathApproaches to design non-covalent inhibitors for human granzyme B (hGrB).Autoantigens: the critical partner in initiating and propagating systemic autoimmunity.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Mechanisms of granule-dependent killing.The possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease.Expression of multiple granzymes by cytotoxic T lymphocyte implies that they activate diverse apoptotic pathways in target cells.The perforin pore facilitates the delivery of cationic cargos.Design and characterization of a novel human Granzyme B inhibitor.Granzyme M: characterization with sites of post-translational modification and specific sites of interaction with substrates and inhibitors.Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program.Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.Design of human granzyme B variants resistant to serpin B9
P2860
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P2860
Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@ast
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@en
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@nl
type
label
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@ast
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@en
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@nl
prefLabel
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@ast
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@en
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of the caspa ...... specific for an Asp-P1 residue
@en
P2093
D Belorgey
E Estébanez-Perpiña
P Fuentes-Prior
R Kiefersauer
P2860
P304
P356
10.1515/BC.2000.148
P577
2000-12-01T00:00:00Z