Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells
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Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidaseCharacterization of a human core-specific lysosomal {alpha}1,6-mannosidase involved in N-glycan catabolism.Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitorInsights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediatesStructural framework of fructosyl transfer in Bacillus subtilis levansucraseProbing the Substrate Specificity of Golgi α-Mannosidase II by Use of Synthetic Oligosaccharides and a Catalytic Nucleophile MutantGolgi -mannosidase II cleaves two sugars sequentially in the same catalytic siteDivergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut FloraThe Molecular Basis of Inhibition of Golgi α-Mannosidase II by Mannostatin ADiscovery and structural characterization of a novel glycosidase family of marine originExploring the molecular pathogenesis and biomarkers of high risk oral premalignant lesions on the basis of long noncoding RNA expression profiling by serial analysis of gene expression.A deletion in the golgi alpha-mannosidase II gene of Caenorhabditis elegans results in unexpected non-wild-type N-glycan structuresMutations in four glycosyl hydrolases reveal a highly coordinated pathway for rhodopsin biosynthesis and N-glycan trimming in Drosophila melanogaster.A long-wavelength fluorescent substrate for continuous fluorometric determination of alpha-mannosidase activity: resorufin alpha-D-mannopyranoside.Abnormal glycosylation of red cell membrane band 3 in the congenital disorder of glycosylation Ig.Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus-ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptorReduced immunogenicity of Arabidopsis hgl1 mutant N-glycans caused by altered accessibility of xylose and core fucose epitopes.A hydrophobic platform as a mechanistically relevant transition state stabilising factor appears to be present in the active centre of all glycoside hydrolases.Drosophila melanogaster cellular repressor of E1A-stimulated genes is a lysosomal protein essential for fly developmentA Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin.In situ structural analysis of Golgi intracisternal protein arrays.Impact of Hybrid and Complex N-Glycans on Cell Surface Targeting of the Endogenous Chloride Cotransporter Slc12a2.Crystallization and preliminary X-ray analysis of cytosolic alpha-mannosidase from Thermotoga maritimaMolecular cloning and functional characterization of a Lepidopteran insect beta4-N-acetylgalactosaminyltransferase with broad substrate specificity, a functional role in glycoprotein biosynthesis, and a potential functional role in glycolipid biosynCrystallization of Saccharomyces cerevisiae alpha-mannosidase, a cargo protein of the Cvt pathway.The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience.Cloning, Expression, and Characterization of Capra hircus Golgi α-Mannosidase II.Structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in ligand-protein interactions.From natural product-inspired pyrrolidine scaffolds to the development of new human Golgi α-mannosidase II inhibitors.Inhibition of Golgi mannosidase II with mannostatin A analogues: synthesis, biological evaluation, and structure-activity relationship studies.GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis.The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors.Molecular identification of family 38 alpha-mannosidase of Bacillus sp. strain GL1, responsible for complete depolymerization of xanthan.Human lysosomal alpha-mannosidases exhibit different inhibition and metal binding propertiesGlycoprotein structural genomics: solving the glycosylation problem.Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.Intracellular transport of human lysosomal alpha-mannosidase and alpha-mannosidosis-related mutants.Automating crystallographic structure solution and refinement of protein-ligand complexes.Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylglucExpression, purification and preliminary crystallographic analysis of Drosophila melanogaster lysosomal α-mannosidase.
P2860
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P2860
Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@ast
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@en
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@nl
type
label
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@ast
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@en
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@nl
prefLabel
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@ast
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@en
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@nl
P2860
P356
P1433
P1476
Structure of Golgi alpha-manno ...... and metastasis of cancer cells
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/20.12.3008
P407
P577
2001-06-01T00:00:00Z