Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
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Crystal Structure of (+)-δ-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for CatalysisStructure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates ,Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi -Isozizaene SynthaseHedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanismA high-throughput colorimetric screening assay for terpene synthase activity based on substrate consumptionExperimental and Theoretical Studies on Corvol Ether Biosynthesis.Mechanistic investigations on six bacterial terpene cyclasesSelectivity of fungal sesquiterpene synthases: role of the active site's H-1 alpha loop in catalysisExpression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesisTraversing the fungal terpenome.Sesquiterpene synthases: passive catalysts or active players?Electrophilic and nucleophilic enzymatic cascade reactions in biosynthesis.The variability of sesquiterpenes emitted from two Zea mays cultivars is controlled by allelic variation of two terpene synthase genes encoding stereoselective multiple product enzymes.Surrogate splicing for functional analysis of sesquiterpene synthase genes.Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneolVolatile terpenes from actinomycetes: a biosynthetic study correlating chemical analyses to genome data.Mutagenesis approaches to deduce structure-function relationships in terpene synthases.Functional analysis of (4S)-limonene synthase mutants reveals determinants of catalytic outcome in a model monoterpene synthase.Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerusVolatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers.Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistryTerpenoid synthase structures: a so far incomplete view of complex catalysis.Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.Moonlighting Metals: Insights into Regulation of Cyclization Pathways in Fungal Δ(6) -Protoilludene Sesquiterpene Synthases.Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture.A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilisPurification, crystallization and preliminary X-ray diffraction analysis of Omp6, a protoilludene synthase from Omphalotus oleariusGeneral base-general acid catalysis by terpenoid cyclases.Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate.A versatile photoactivatable probe designed to label the diphosphate binding site of farnesyl diphosphate utilizing enzymes.Biosynthesis via carbocations: theoretical studies on terpene formation.Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis.Walking in the woods with quantum chemistry--applications of quantum chemical calculations in natural products research.Bacterial terpene cyclases.Importance of Inherent Substrate Reactivity in Enzyme-Promoted Carbocation Cyclization/Rearrangements.Conformational Analysis, Thermal Rearrangement, and EI-MS Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by (13)C-Labeling Experiments.Structural and Chemical Biology of Terpenoid Cyclases.Genome of Diaporthe sp. provides insights into the potential inter-phylum transfer of a fungal sesquiterpenoid biosynthetic pathway.Trinuclear Metal Clusters in Catalysis by Terpenoid Synthases.Knock-down of the methyltransferase Kmt6 relieves H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi.
P2860
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P2860
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@ast
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@en
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@nl
type
label
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@ast
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@en
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@nl
prefLabel
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@ast
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@en
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@nl
P2093
P3181
P356
P1476
Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis
@en
P2093
Chiana M Paschall
David E Cane
David W Christianson
Guangzhi Zhai
Jan-Willem de Kraker
Myriam Seemann
P304
P3181
P356
10.1021/JA026058Q
P407
P577
2002-07-03T00:00:00Z