ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis
about
A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzymeCoupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymesThe SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterizationA crucial role in fertility for the oyster angiotensin-converting enzyme orthologue CgACETrapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysisSwapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidaseStructural Analysis of Major Species Barriers between Humans and Palm Civets for Severe Acute Respiratory Syndrome Coronavirus InfectionsCrystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptorThe Exquisite Structure and Reaction Mechanism of Bacterial Pz-peptidase A toward Collagenous Peptides: X-RAY CRYSTALLOGRAPHIC STRUCTURE ANALYSIS OF PZ-PEPTIDASE A REVEALS DIFFERENCES FROM MAMMALIAN THIMET OLIGOPEPTIDASEStructural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1Structural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent EndopeptidaseCrystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation MechanismStructural basis for multifunctional roles of mammalian aminopeptidase NMultiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidaseAdvances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular functionSevere acute respiratory syndrome coronavirus as an agent of emerging and reemerging infectionInhibition mechanism and model of an angiotensin I-converting enzyme (ACE)-inhibitory hexapeptide from yeast (Saccharomyces cerevisiae)A global comparison of the human and T. brucei degradomes gives insights about possible parasite drug targetsInteraction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2.The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor bindingIdentification and characterisation of the angiotensin converting enzyme-3 (ACE3) gene: a novel mammalian homologue of ACE.Structure, Function, and Evolution of Coronavirus Spike Proteins.Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure.Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry.Prediction of off-target effects on angiotensin-converting enzyme 2.ACE for all - a molecular perspectiveAngiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling.Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent.Allosteric inhibition of the neuropeptidase neurolysin.Cross-crystal averaging with search models to improve molecular replacement phases.ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.Receptor recognition mechanisms of coronaviruses: a decade of structural studies.Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assaysAngiotensin-converting enzyme 2: the first decade.Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system.Biosynthetic pathways and the role of the MAS receptor in the effects of Angiotensin-(1-7) in smooth muscles.Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirusStructure of testis ACE glycosylation mutants and evidence for conserved domain movement.Antivirals and antiviral strategies.Evidence for ACE2-utilizing coronaviruses (CoVs) related to severe acute respiratory syndrome CoV in bats.
P2860
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P2860
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@ast
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@en
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@nl
type
label
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@ast
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@en
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@nl
prefLabel
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@ast
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@en
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@nl
P2093
P2860
P356
P1476
ACE2 X-ray structures reveal a ...... nhibitor binding and catalysis
@en
P2093
Bart Staker
David Williams
Dominic Ryan
Martin Fisher
Michael A Patane
Michael W Pantoliano
Natalie A Dales
Paul Towler
Saurabh Menon
P2860
P304
17996-8007
P356
10.1074/JBC.M311191200
P407
P577
2004-04-23T00:00:00Z