Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin - sprookjes - yvandenbroek - TriplyDB

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin

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Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding Region Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies.Yeast surface display for protein engineering and characterization An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity A decade of yeast surface display technology: where are we now?Thermostable llama single domain antibodies for detection of botulinum A neurotoxin complex Back to the future: recombinant polyclonal antibody therapeutics.Quantitative specificity-based display library screening identifies determinants of antibody-epitope binding specificity Bacterial display enables efficient and quantitative peptide affinity maturation.Specificity tuning of antibody fragments to neutralize two human chemokines with a single agent Llama single domain antibodies specific for the 7 botulinum neurotoxin serotypes as heptaplex immunoreagents.Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating.Progress towards recombinant anti-infective antibodies.Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents.Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS.RBC Adherence of Immune Complexes Containing Botulinum Toxin Improves Neutralization and Macrophage Uptake.Particle display: a quantitative screening method for generating high-affinity aptamers.Beyond natural antibodies: the power of in vitro display technologies.Vaccination of rabbits with an alkylated toxoid rapidly elicits potent neutralizing antibodies against botulinum neurotoxin serotype B.Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity.Bacterial display in combinatorial protein engineering.Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals.Domain-based assays of individual antibody concentrations in an oligoclonal combination targeting a single protein.Surface display of a single-domain antibody library on Gram-positive bacteria.Using phage and yeast display to select hundreds of monoclonal antibodies: application to antigen 85, a tuberculosis biomarker.Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin Rapid optimization and prototyping for therapeutic antibody-like molecules.Rational engineering of a human anti-dengue antibody through experimentally validated computational docking.Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment Studies of the mechanistic details of the pH-dependent association of botulinum neurotoxin with membranes Antibody engineering for increased potency, breadth and half-life.Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity Epitope characterization of sero-specific monoclonal antibody to Clostridium botulinum neurotoxin type A Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8 Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.

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Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin

http://www.wikidata.org/entity/Q27643327

description

2007 nî lūn-bûn

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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2007年の論文

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Nature Biotechnology

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Molecular evolution of antibod ...... of type A botulinum neurotoxin

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Ali Razai

http://www.w3.org/2001/XMLSchema#string

Charles M Forsyth

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Consuelo Garcia-Rodriguez

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Isin Geren

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James D Marks

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Jianlong Lou

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Joseph W Arndt

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Raphael Levy

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Raymond C Stevens

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Botulinum Toxin as a Biological Weapon: Medical and Public Health Management

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Processing of X-ray diffraction data collected in oscillation mode

Antibody multispecificity mediated by conformational diversity

Crystal structure of botulinum neurotoxin type A and implications for toxicity

Coot: model-building tools for molecular graphics

ESPript: analysis of multiple sequence alignments in PostScript

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

Yeast recombination: the association between double-strand gap repair and crossing-over

MOLREP: an Automated Program for Molecular Replacement

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107-16

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scholarly article

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4780083

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10.1038/NBT1269

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1

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25

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2007-01-01T00:00:00Z

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6627128

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1020542853

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17173035

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