An Engineered Second Disulfide Bond Restricts Lymphotactin/XCL1 to a Chemokine-like Conformation with XCR1 Agonist Activity † - sprookjes - yvandenbroek - TriplyDB

An Engineered Second Disulfide Bond Restricts Lymphotactin/XCL1 to a Chemokine-like Conformation with XCR1 Agonist Activity †

An Engineered Second Disulfide Bond Restricts Lymphotactin/XCL1 to a Chemokine-like Conformation with XCR1 Agonist Activity †

http://www.wikidata.org/entity/Q27643823

about

Native-state interconversion of a metamorphic protein requires global unfolding Interconversion between two unrelated protein folds in the lymphotactin native state SAD phasing using iodide ions in a high-throughput structural genomics environment Structural insight into the evolution of a new chemokine family from zebrafish Dynamic interchanging native states of lymphotactin examined by SNAPP-MS Structural gymnastics of multifunctional metamorphic proteins.Proteins that switch folds Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily.The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1.The Identification and Distribution of Cattle XCR1 and XCL1 among Peripheral Blood Cells: New Insights into the Design of Dendritic Cells Targeted Veterinary Vaccine.Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation Targeting Influenza Virus Hemagglutinin to Xcr1+ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses.Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approach.Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein.Chapter 3. Lymphotactin structural dynamics.Molecular vaccine prepared by fusion of XCL1 to the multi-epitope protein of foot-and-mouth disease virus enhances the specific humoural immune response in cattle.Sulfotyrosine recognition as marker for druggable sites in the extracellular space.The association and aggregation of the metamorphic chemokine lymphotactin with fondaparinux: from nm molecular complexes to μm molecular assemblies

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P2860

An Engineered Second Disulfide Bond Restricts Lymphotactin/XCL1 to a Chemokine-like Conformation with XCR1 Agonist Activity †

http://www.wikidata.org/entity/Q27643823

description

2007 nî lūn-bûn

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2007 թուականի Մարտին հրատարակուած գիտական յօդուած

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2007 թվականի մարտին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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type

label

An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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An Engineered Second Disulfide ...... n with XCR1 Agonist Activity †

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Adam J Pelzek

http://www.w3.org/2001/XMLSchema#string

Brian F Volkman

http://www.w3.org/2001/XMLSchema#string

E Sonay Elgin

http://www.w3.org/2001/XMLSchema#string

Francis C Peterson

http://www.w3.org/2001/XMLSchema#string

Robbyn L Tuinstra

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of viral macrophage inflammatory protein (vMIP)-II as a ligand for GPR5/XCR1

Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions

Identification of single C motif-1/lymphotactin receptor XCR1

Molecular cloning and functional characterization of human lymphotactin

Lymphotactin is produced by NK cells and attracts both NK cells and T cells in vivo

Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype

Monomeric solution structure of the prototypical 'C' chemokine lymphotactin

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

Refinement of protein structures in explicit solvent

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2564-73

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10.1021/BI602365D

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