Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating
about
Emerging models of glutamate receptor ion channel structure and functionComputational study of synthetic agonist ligands of ionotropic glutamate receptorsMolecular mechanism of ligand recognition by NR3 subtype glutamate receptorsCorrelating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists †Stability of ligand-binding domain dimer assembly controls kainate receptor desensitizationEnhanced Efficacy without Further Cleft Closure: Reevaluating Twist as a Source of Agonist Efficacy in AMPA ReceptorsMechanisms of Modal Activation of GluA3 ReceptorsStructural and Functional Analysis of Two New Positive Allosteric Modulators of GluA2 Desensitization and DeactivationMechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONSThe Loss of an Electrostatic Contact Unique to AMPA Receptor Ligand Binding Domain 2 Slows Channel ActivationModulation of non-NMDA receptor gating by auxiliary subunitsGlutamate receptor ion channels: structure, regulation, and functionGluN1-specific redox effects on the kinetic mechanism of NMDA receptor activationAuxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor FunctionGating modes in AMPA receptors.Characterizing single-channel behavior of GluA3 receptorsStargazin promotes closure of the AMPA receptor ligand-binding domainThe hidden energetics of ligand binding and activation in a glutamate receptorStructural landscape of isolated agonist-binding domains from single AMPA receptorsAuxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors.Agonist-specific gating of NMDA receptors.Probing TARP modulation of AMPA receptor conductance with polyamine toxins.Structure of an agonist-bound ionotropic glutamate receptorAtomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptorRole of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism.Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits.Kinetic basis of partial agonism at NMDA receptors.Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution.Molecular lock regulates binding of glycine to a primitive NMDA receptor.What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor.Structure and gating of tetrameric glutamate receptors.Retour aux sources: defining the structural basis of glutamate receptor activation.TARP-associated AMPA receptors display an increased maximum channel conductance and multiple kinetically distinct open states.Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation.Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum.A quantum biochemistry investigation of willardiine partial agonism in AMPA receptors.Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation.Accessories assist AMPA receptors to close pockets.Mechanism of partial agonism in AMPA-type glutamate receptors.Defining the structural relationship between kainate-receptor deactivation and desensitization
P2860
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P2860
Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural and single-channel ...... ly impact AMPA receptor gating
@ast
Structural and single-channel ...... ly impact AMPA receptor gating
@en
Structural and single-channel ...... ly impact AMPA receptor gating
@nl
type
label
Structural and single-channel ...... ly impact AMPA receptor gating
@ast
Structural and single-channel ...... ly impact AMPA receptor gating
@en
Structural and single-channel ...... ly impact AMPA receptor gating
@nl
prefLabel
Structural and single-channel ...... ly impact AMPA receptor gating
@ast
Structural and single-channel ...... ly impact AMPA receptor gating
@en
Structural and single-channel ...... ly impact AMPA receptor gating
@nl
P2093
P1476
Structural and single-channel ...... ly impact AMPA receptor gating
@en
P2093
James R Howe
Yoonsang Cho
P304
P356
10.1523/JNEUROSCI.3309-07.2008
P407
P50
P577
2008-01-01T00:00:00Z