Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A
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Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor.Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes.PRIP (phospholipase C-related but catalytically inactive protein) inhibits exocytosis by direct interactions with syntaxin 1 and SNAP-25 through its C2 domain.Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells.Translating neuronal activity at the synapse: presynaptic calcium sensors in short-term plasticity.Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate.Synergistic effect of Pb(2+) and phosphatidylinositol 4,5-bisphosphate on C2 domain-membrane interactions.NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomes.Presynaptic congenital myasthenic syndrome with altered synaptic vesicle homeostasis linked to compound heterozygous sequence variants in RPH3A.RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.Distinctive phosphoinositide and Ca2+ binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
P2860
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P2860
Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@ast
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@en
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@nl
type
label
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@ast
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@en
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@nl
prefLabel
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@ast
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@en
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@nl
P2860
P50
P356
P1476
Structural determinants for Ca ...... the C2A domain of rabphilin-3A
@en
P2093
Andrei Leonov
Stefan Becker
P2860
P304
P356
10.1074/JBC.M804094200
P407
P577
2008-12-19T00:00:00Z