A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
about
Monoclonal antibodies for the treatment of cancerFocus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.Extracellular matrix molecules: potential targets in pharmacotherapy.Monoclonal antibodies: versatile platforms for cancer immunotherapy.Phage displayed peptides/antibodies recognizing growth factors and their tyrosine kinase receptors as tools for anti-cancer therapeutics.Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice.Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms.Trial Watch: Immunostimulatory cytokines.Statistical database analysis of the role of loop dynamics for protein-protein complex formation and allostery.The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisStructural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily.New horizons in therapeutic antibody discovery: opportunities and challenges versus small-molecule therapeutics.Structural Biology and Evolution of the TGF-β FamilyFeasibility of implementing cell-based pathway reporter assays in early high-throughput screening assay cascades for antibody drug discovery.A Targeted Multiple Antigenic Peptide Vaccine Augments the Immune Response to Self TGF-β1 and Suppresses Ongoing Hepatic Fibrosis.Biological activity differences between TGF-β1 and TGF-β3 correlate with differences in the rigidity and arrangement of their component monomers.Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions.Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody.Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro.
P2860
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P2860
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@ast
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@en
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@nl
type
label
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@ast
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@en
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@nl
prefLabel
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@ast
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@en
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@nl
P2093
P2860
P921
P3181
P356
P1476
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
@en
P2093
Christian Grütter
Donna Finch
Lutz Jermutus
Markus G Grütter
Matthew McCourt
Richard Turner
Sadhana Podichetty
Scott Loning
Trevor Wilkinson
P2860
P304
P3181
P356
10.1073/PNAS.0807200106
P407
P577
2008-12-23T00:00:00Z