about
Prion strains and amyloid polymorphism influence phenotypic variationUbiquitous amyloidsSynthetic prions with novel strain-specified propertiesMapping the conformational dynamics and pathways of spontaneous steric zipper Peptide oligomerizationMinimalist design of water-soluble cross-beta architecture.Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Diseaseβ2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkagesAtomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion DiseaseStructures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formationCharacteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet MimicsStructure-based design of non-natural amino-acid inhibitors of amyloid fibril formationTowards a Pharmacophore for AmyloidMolecular basis for amyloid- polymorphismCrystal Structure of a Human Prion Protein Fragment Reveals a Motif for Oligomer FormationStructure and dynamics of amyloid-β segmental polymorphismsCommon features at the start of the neurodegeneration cascadeDefining the conformational features of anchorless, poorly neuroinvasive prionsThe effect of β2-α2 loop mutation on amyloidogenic properties of the prion proteinSpontaneous variants of the [RNQ+] prion in yeast demonstrate the extensive conformational diversity possible with prion proteinsInter-species cross-seeding: stability and assembly of rat-human amylin aggregatesCryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibrilRecent progress in understanding Alzheimer's β-amyloid structures.Glutamine and Asparagine Side Chain Hyperconjugation-Induced Structurally Sensitive Vibrations.Protein structure along the order-disorder continuumConsidering protonation as a posttranslational modification regulating protein structure and function.Polymorphism of β2-microglobulin amyloid fibrils manifested by ultrasonication-enhanced fibril formation in trifluoroethanolGlobular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversionSelenomethionine incorporation into amyloid sequences regulates fibrillogenesis and toxicityTwo amyloid States of the prion protein display significantly different folding patternsHuman prion protein sequence elements impede cross-species chronic wasting disease transmission.The Surprising Role of Amyloid Fibrils in HIV InfectionDistinct prion strains are defined by amyloid core structure and chaperone binding site dynamics.Identifying the amylome, proteins capable of forming amyloid-like fibrilsPrinciples governing oligomer formation in amyloidogenic peptides.Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.The protein kingdom extended: ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation.Amyloid structure: conformational diversity and consequences.Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicityThe tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.Proteomics analysis of amyloid and nonamyloid prion disease phenotypes reveals both common and divergent mechanisms of neuropathogenesis
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Molecular mechanisms for protein-encoded inheritance
@ast
Molecular mechanisms for protein-encoded inheritance
@en
Molecular mechanisms for protein-encoded inheritance
@nl
type
label
Molecular mechanisms for protein-encoded inheritance
@ast
Molecular mechanisms for protein-encoded inheritance
@en
Molecular mechanisms for protein-encoded inheritance
@nl
prefLabel
Molecular mechanisms for protein-encoded inheritance
@ast
Molecular mechanisms for protein-encoded inheritance
@en
Molecular mechanisms for protein-encoded inheritance
@nl
P2093
P2860
P50
P356
P1476
Molecular mechanisms for protein-encoded inheritance
@en
P2093
Angela B Soriaga
Jed J W Wiltzius
Kanagalaghatta Rajashankar
Lukasz Goldschmidt
Marcin I Apostol
Rebecca Nelson
P2860
P2888
P356
10.1038/NSMB.1643
P577
2009-09-01T00:00:00Z
P5875
P6179
1051653779