Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E
about
Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesUncovering viral protein-protein interactions and their role in arenavirus life cyclePathogenesis of Lassa feverCrystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repressionStructural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4EStructure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4GTargeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activityA biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery.Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacementMolecular mechanism of arenavirus assembly and budding.Multifunctional nature of the arenavirus RING finger protein Z.A systems biology starter kit for arenaviruses.eIF4E as a control target for viruses.Genomic profiling of host responses to Lassa virus: therapeutic potential from primate to manMolecular determinants of arenavirus Z protein homo-oligomerization and L polymerase bindingSingle nucleoprotein residue modulates arenavirus replication complex formation.Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex.The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.Influence of RNA Binding on the Structure and Dynamics of the Lassa Virus Nucleoprotein.The oncogene eIF4E: using biochemical insights to target cancer.Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever.Potential therapeutic applications of RNA cap analogs.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Arenavirus budding resulting from viral-protein-associated cell membrane curvature.Arenavirus buddingThe eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.Conserved residues in Lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoproteinHypoxia induces the gene expression and extracellular transmission of persistent lymphocytic choriomeningitis virus.Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z.Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.Cell biology. Puzzled by PML.A proteomic survey of Junín virus interactions with human proteins reveals host factors required for arenavirus replication.A Highly Conserved Leucine In Mammarenavirus Matrix Z Protein Is Required For Z Interaction With The Virus L Polymerase And Z Stability In Cells Harboring An Active Viral Ribonucleoprotein.Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
P2860
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P2860
Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Structural characterization of ...... inct mode of control for eIF4E
@ast
Structural characterization of ...... inct mode of control for eIF4E
@en
Structural characterization of ...... inct mode of control for eIF4E
@nl
type
label
Structural characterization of ...... inct mode of control for eIF4E
@ast
Structural characterization of ...... inct mode of control for eIF4E
@en
Structural characterization of ...... inct mode of control for eIF4E
@nl
prefLabel
Structural characterization of ...... inct mode of control for eIF4E
@ast
Structural characterization of ...... inct mode of control for eIF4E
@en
Structural characterization of ...... inct mode of control for eIF4E
@nl
P2093
P2860
P3181
P356
P1476
Structural characterization of ...... inct mode of control for eIF4E
@en
P2093
Althea A Capul
Juan C de la Torre
Katherine L B Borden
Laurent Volpon
Michael J Osborne
P2860
P304
P3181
P356
10.1073/PNAS.0909877107
P407
P577
2010-03-23T00:00:00Z