Structure-based development of a receptor activator of nuclear factor- B ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
about
Principles of antibody-mediated TNF receptor activationRANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy ReceptorDimerization of LT R by LT 1 2 is necessary and sufficient for signal transductionThe methionine-aromatic motif plays a unique role in stabilizing protein structure.DR6 as a diagnostic and predictive biomarker in adult sarcoma.Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL.Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily membersRANK-dependent autosomal recessive osteopetrosis: characterization of five new cases with novel mutationsGlucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients?Binding efficiency of protein-protein complexes.Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding AffinityRANKL cytokine: from pioneer of the osteoimmunology era to cure for a rare diseaseStructure based antibody-like peptidomimetics.Osteopetrosis: genetics, treatment and new insights into osteoclast function.Osteoclast differentiation inhibitors: a patent review (2008 - 2012).Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures.Inhibition effect of enteropeptidase on RANKL-RANK signalling by cleavage of RANK.The emerging role of Hippo signaling pathway in regulating osteoclast formation.Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis.Improved efficacy of soluble human receptor activator of nuclear factor kappa B (RANK) fusion protein by site-directed mutagenesis.Novel RANK antagonists for the treatment of bone-resorptive disease: theoretical predictions and experimental validation.A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF
P2860
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P2860
Structure-based development of a receptor activator of nuclear factor- B ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure-based development of ...... ecular basis for osteopetrosis
@ast
Structure-based development of ...... ecular basis for osteopetrosis
@en
Structure-based development of ...... ecular basis for osteopetrosis
@nl
type
label
Structure-based development of ...... ecular basis for osteopetrosis
@ast
Structure-based development of ...... ecular basis for osteopetrosis
@en
Structure-based development of ...... ecular basis for osteopetrosis
@nl
prefLabel
Structure-based development of ...... ecular basis for osteopetrosis
@ast
Structure-based development of ...... ecular basis for osteopetrosis
@en
Structure-based development of ...... ecular basis for osteopetrosis
@nl
P2093
P2860
P356
P1476
Structure-based development of ...... ecular basis for osteopetrosis
@en
P2093
Hai Minh Ta
Hye Mi Jin
Hye-Yeon Hwang
Hyejin Park
Jongkeun Choi
Kyeong Kyu Kim
Nacksung Kim
P2860
P304
P356
10.1073/PNAS.1011686107
P407
P577
2010-11-23T00:00:00Z