NMR spectroscopy and molecular dynamics simulation of r(CCGCUGCGG)₂ reveal a dynamic UU internal loop found in myotonic dystrophy type 1.
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Structural studies of CNG repeatsA Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X SyndromeUtilizing the GAAA Tetraloop/Receptor To Facilitate Crystal Packing and Determination of the Structure of a CUG RNA HelixMyotonic Dystrophy Type 1 RNA Crystal Structures Reveal Heterogeneous 1 × 1 Nucleotide UU Internal Loop ConformationsA dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations.Trinucleotide repeats: a structural perspectiveComputational investigation of RNA CUG repeats responsible for myotonic dystrophy 1Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor.Methods to enable the design of bioactive small molecules targeting RNA.Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.Features of modularly assembled compounds that impart bioactivity against an RNA target.Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)RNA Structures as Mediators of Neurological Diseases and as Drug Targets.On the Applicability of Elastic Network Models for the Study of RNA CUG Trinucleotide Repeat Overexpansion.Investigating the binding mode of an inhibitor of the MBNL1·RNA complex in myotonic dystrophy type 1 (DM1) leads to the unexpected discovery of a DNA-selective binder.Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts.Functional Rescue of F508del-CFTR Using Small Molecule CorrectorsStructure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1.
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P2860
NMR spectroscopy and molecular dynamics simulation of r(CCGCUGCGG)₂ reveal a dynamic UU internal loop found in myotonic dystrophy type 1.
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2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
NMR Spectroscopy and Molecular ...... d in Myotonic Dystrophy Type 1
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NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
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NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
@en
type
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NMR Spectroscopy and Molecular ...... d in Myotonic Dystrophy Type 1
@nl
NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
@ast
NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
@en
prefLabel
NMR Spectroscopy and Molecular ...... d in Myotonic Dystrophy Type 1
@nl
NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
@ast
NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
@en
P2093
P2860
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NMR spectroscopy and molecular ...... in myotonic dystrophy type 1.
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P2093
Matthew D Disney
Matthew Fountain
Raman Parkesh
P2860
P304
P3181
P356
10.1021/BI101896J
P407
P577
2011-01-13T00:00:00Z