Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
about
High-resolution crystal structure of Streptococcus pyogenes β-NAD + glycohydrolase in complex with its endogenous inhibitor IFS reveals a highly water-rich interfaceAn interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cellsInterrupting peptidoglycan deacetylation during Bdellovibrio predator-prey interaction prevents ultimate destruction of prey wall, liberating bacterial-ghosts.The natural history of ADP-ribosyltransferases and the ADP-ribosylation system.The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NADDual modes of membrane binding direct pore formation by Streptolysin O.Analysis of polymorphic residues reveals distinct enzymatic and cytotoxic activities of the Streptococcus pyogenes NAD+ glycohydrolase.Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus.Crystallization and preliminary X-ray analysis of two variants of the Escherichia coli O157 ParE2-PaaA2 toxin-antitoxin complex.PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.Mapping the protein-protein interface between a toxin and its cognate antitoxin from the bacterial pathogen Streptococcus pyogenesNAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains.
P2860
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P2860
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@ast
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@en
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@nl
type
label
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@ast
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@en
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@nl
prefLabel
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@ast
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@en
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@nl
P2093
P2860
P50
P3181
P1433
P1476
Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase Toxin
@en
P2093
Craig L Smith
Jerome S Pinkner
Joydeep Ghosh
Michael G Caparon
P2860
P304
P3181
P356
10.1016/J.STR.2010.12.013
P577
2011-02-09T00:00:00Z