Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins
about
Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal EffectsApplications of small molecule probes in dissecting mechanisms of bacterial virulence and host responsesClostridial toxins: sensing a target in a hostile gut environment.Conformational analysis of Clostridium difficile toxin B and its implications for substrate recognitionClostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanismAllosteric Inhibition of a Zinc-Sensing Transcriptional Repressor: Insights into the Arsenic Repressor (ArsR) FamilyThe structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein fromClostridium difficileCritical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides.Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome.Clostridium difficile toxins: mediators of inflammation.Toward a structural understanding of Clostridium difficile toxins A and B.Super toxins from a super bug: structure and function of Clostridium difficile toxins.Immunization strategies for Clostridium difficile infections.Comparative structural analysis of the caspase family with other clan CD cysteine peptidases.Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.Small Molecules That Sabotage Bacterial Virulence.Cytotoxicity of Clostridium difficile toxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol.A small-molecule antivirulence agent for treating Clostridium difficile infection.TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing.The role of toxins in Clostridium difficile infection.Treatment of Clostridium difficile infection with a small molecule inhibitor of toxin UDP-glucose hydrolysis activity.On and Off: A Dual Role for Cysteine Protease Autoprocessing of C difficile Toxin B on Cytotoxicity vs Proinflammatory Toxin Actions?Cysteine Protease-Mediated Autocleavage of Clostridium difficile Toxins Regulates Their Proinflammatory Activity.Novel Chimeric Protein Vaccines Against Infection
P2860
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P2860
Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
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2011年論文
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2011年论文
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name
Defining an allosteric circuit ...... f Clostridium difficile toxins
@ast
Defining an allosteric circuit ...... f Clostridium difficile toxins
@en
Defining an allosteric circuit ...... f Clostridium difficile toxins
@nl
type
label
Defining an allosteric circuit ...... f Clostridium difficile toxins
@ast
Defining an allosteric circuit ...... f Clostridium difficile toxins
@en
Defining an allosteric circuit ...... f Clostridium difficile toxins
@nl
prefLabel
Defining an allosteric circuit ...... f Clostridium difficile toxins
@ast
Defining an allosteric circuit ...... f Clostridium difficile toxins
@en
Defining an allosteric circuit ...... f Clostridium difficile toxins
@nl
P2093
P2860
P3181
P356
P1476
Defining an allosteric circuit ...... f Clostridium difficile toxins
@en
P2093
Aaron W Puri
Aimee Shen
K Christopher Garcia
Malte M Gersch
Patrick J Lupardus
Victoria E Albrow
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1990
P577
2011-03-01T00:00:00Z
P5875
P6179
1021126809